Results 91 to 100 of about 10,780,423 (379)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Weak solutions and optimal controls of stochastic fractional reaction-diffusion systems

open access: yesOpen Mathematics, 2020
The aim of this paper is to investigate a class of nonlinear stochastic reaction-diffusion systems involving fractional Laplacian in a bounded domain. First, the existence and uniqueness of weak solutions are proved by using Galërkin’s method.
Fu Yongqiang, Yan Lixu
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Weak vorticity formulation for the incompressible Euler equations in domains with boundary

open access: yes, 2013
In this article we examine the interaction of incompressible 2D flows with compact material boundaries. Our focus is the dynamic behavior of the circulation of velocity around boundary components and the possible exchange between flow vorticity and ...
Filho, Milton Lopes   +3 more
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Regularity criteria for weak solutions to 3D incompressible MHD equations with Hall term

open access: yesElectronic Journal of Differential Equations, 2018
We study the regularity conditions for a weak solution to the incompressible 3D magnetohydrodynamic equations with Hall term in the whole space R^3. In particular, we show the regularity criteria in view of gradient vectors in various spaces.
Jae-Myoung Kim
doaj  

Global weak solution to the viscous two-fluid model with finite energy [PDF]

open access: yesJournal des Mathématiques Pures et Appliquées, 2017
A. Vasseur, Huanyao Wen, Cheng Yu
semanticscholar   +1 more source

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