Results 91 to 100 of about 2,496,982 (281)
Conservation laws. II: Weak solutions
, 2007 Summary: For parts I and III see [ibid. 81--90 (2007; Zbl 1156.35428)] and ibid. 107--115 (2007; Zbl 1156.35425)]. We apply the maximum principle and the compensated compactness method to get the existence of weak solutions to the Cauchy problems for the nonlinear hyperbolic conservation laws of quadratic flux and the LeRoux system with sources.
TAO, MING, CHENG, ZHIXIN, YAN, JIN
openaire +2 more sources
Non-Smooth Stochastic Lyapunov Functions With Weak Extension of Viscosity Solutions
, 2019 This paper proposes a notion of viscosity weak supersolutions to build a bridge between stochastic Lyapunov stability theory and viscosity solution theory.
Hoshino, Kenta, Nishimura, Yuki
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Solutions for p(x)-Laplace equations with critical frequency
Electronic Journal of Differential Equations, 2018 This article concerns the p(x)-Laplace equations with critical frequency $$ -\text{div}(|\nabla u|^{p(x)-2}\nabla u)+V(x)|u|^{p(x)-2}u=f(x,u)\quad \text{in } \mathbb{R}^N, $$ where ...
Xia Zhang, Chao Zhang, Huimin Gao
doaj
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Weak solutions for quasilinear degenerate parabolic systems
Electronic Journal of Differential Equations, 2006 This paper concerns the initial Dirichlet boundary-value problem for a class of quasilinear degenerate parabolic systems. Due to the degeneracies, the problem does not have classical solutions in general.
Zheng'an Yao, Wenshu Zhou
doaj
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Weak solution of the nonuniform multiconductor transmission lines [PDF]
, 1998 Canavero, Flavio, Grivet-Talocia, S.
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source