Results 41 to 50 of about 111,103 (317)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Study on Wear Resistance and Corrosion Resistance of HVOF Surface Coating Refabricate for Hydraulic Support Column [PDF]

open access: yes, 2021
The hydraulic support column bears loading and makes reciprocating motion ceaselessly for extended periods, so its service life is far shorter than that of the overall hydraulic support.
Tian Yang   +6 more
core   +1 more source

Microstructure, high-temperature cyclic oxidation, and hot corrosion behaviors of Inconel 718 alloy produced by laser-induction hybrid cladding

open access: yesJournal of Materials Research and Technology
The microstructure evolution, cyclic oxidation, and hot corrosion behavior of the unheated-treated (As-built) and solution + double aging (SDA)-treated Inconel 718 alloys fabricated through laser-induction hybrid cladding (LIHC) were investigated. It was
Lei Qin   +7 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The wear behaviour of ion implanted biomaterials [PDF]

open access: yes, 2003
The tribological performance of biomaterials used for artificial joints is of much importance, and require low coefficients of friction, resistance to wear and the ability to withstand many millions of cycles under a multitude of loading regimes ...
Boampong, Derrick Kwadwo
core  

Micro-abrasion resistance of thermochemically treated steels in aqueous solutions: Mechanisms, maps, materials selection [PDF]

open access: yes, 2008
The area of micro-abrasion is an interesting and relatively recent area in tribo-testing methodologies, where small particles of less than 10 μm are employed between interacting surfaces.
Rocha, L.A.   +7 more
core   +1 more source

Orientation dependence of the wear resistance in the Co–Cr–Mo single crystal [PDF]

open access: yes, 2021
This is the report clarifying the orientation dependence of the wear behavior of Co–Cr–Mo alloy. The wear resistance of the Co–Cr–Mo alloy with face-centered cubic (fcc) structure was found to be higher on the planes in order of {110}, {001} and {111 ...
Hagihara, Koji   +6 more
core   +1 more source

Wear Behavior of Ti-xNb Biomedical Alloys by Ball Cratering [PDF]

open access: yesMaterials Research
Ti alloys have been developing through the years, aiming the biomedical application since it has suitable properties. Among Ti alloys, the Ti-Nb systems are a pronounced group to biomedical applications due to its low elastic modulus, good corrosion ...
Felype N. de Mattos   +3 more
doaj   +1 more source

Profound Leadership Strategies: Transcending the Leadership Crisis in the Age of Artificial Intelligence

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley   +1 more source

A study of the wear process related to twin-screw extruders [PDF]

open access: yes, 1996
Extruders are used in a wide range of process industries and high reliability is essential if cost effective manufacturing is to be maintained. A critical part of twin-screw extruders is the barrel that must withstand many different wear and corrosion ...
Grigoroudis, K.
core  

Home - About - Disclaimer - Privacy