Results 41 to 50 of about 8,468,154 (348)

The template for a Semantic SensorThings API with the GloSIS use case [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Since 2016 the Open Geospatial Consortium (OGC) has embarked on a new specification paradigm for web access to geo-spatial data. Moving on from the SOAP/XML pattern underlying the many web services it specified earlier, the OGC has since issued novel ...
L. M. de Sousa, R. Palma, B. Janiak, P. van Genuchten   +3 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Implementation of clinical research trials using web-based and mobile devices: challenges and solutions

BMC Medical Research Methodology, 2017
Background With the increasing implementation of web-based, mobile health interventions in clinical trials, it is crucial for researchers to address the security and privacy concerns of patient information according to high ethical standards.
Roy Eagleson, Luis Altamirano-Diaz, Alex McInnis, Eva Welisch, Stefanie De Jesus, Harry Prapavessis, Meghan Rombeek, Jamie A. Seabrook, Teresa Park, Kambiz Norozi   +9 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Web Accessibility in Higher Education Institutions of Ecuador: Year 2016

Journal of Science and Research, 2016
This research was conducted in order to establish the progress made by the web accessibility in the pages of higher education institutions verify ing how many of them implement the NTE INEN ISO/IEC40500standard,which establishes accessibility guidelines ...
Nelly Karina Esparza Cruz, Zoila Merino Acosta, Hugo Guerrero Torres   +2 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

What is the current state of the Multilingual Web of Data? [PDF]

, 2012
The Semantic Web is growing at a fast pace, recently boosted by the creation of the Linked Data initiative and principles. Methods, standards, techniques and the state of technology are becoming more mature and therefore are easing the task of ...
Gómez-Pérez, A., Vila-Suero, Daniel
core   +1 more source

GeoServer: il server geospaziale Open Source novità della nuova versione 2.3.0

GEOmedia, 2013
GeoServer è un server geospaziale Open Source sviluppato con tecnologia Java Enterprise per la gestione e l’editing di dati geospaziali secondo gli standard OGC e ISO Technical Committee 211.
Simone Giannecchini, Andrea Aime
doaj   +2 more sources

A Model for Distributed Curriculum on the World Wide Web

Journal of Interactive Media in Education, 1998
Educational material abounds on the Web, but still most designers of instructional material must start from scratch. Emerging interoperability standards for educational resources will accelerate progress toward reusability of this material. We describe
Tom J. Murray
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source