Results 51 to 60 of about 3,721,403 (317)
Semivalues: weighting coefficients and allocations on unanimity games [PDF]
Optimization Letters, 2017 Each semivalue, as a solution concept defined on cooperative games with a finite set of players, is univocally determined by weighting coefficients that apply to players’ marginal contributions. Taking into account that a semivalue induces semivalues on lower cardinalities, we prove that its weighting coefficients can be reconstructed from the last ...
Domènech Blázquez, Margarita +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Monthly runoff prediction using modified CEEMD-based weighted integrated model
Journal of Water and Climate Change, 2021 Due to the nonlinear characteristics of runoff data and the poor performance of the single prediction model, a weighted integrated modified complementary ensemble empirical mode decomposition (MCEEMD)-based model was proposed to predict the monthly ...
Xinqing Yan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Drug Design, Development and Therapy, 2022 Jia Li,1,* Xiao Wang,1,* Shining Xun,2,* Qiuting Guo,3 Yao Wang,1 Yanzuo Jia,1 Wenfei Wang,1 Yujiao Wang,1 Taotao Li,1 Tiantian Tang,1 Junbo Zou,1 Mei Wang,1 Ming Yang,4 Fang Wang,4 Xiaofei Zhang,1,4 Changli Wang1 1Department of Pharmaceutics,
Li J +15 more
doaj
Mathematics, 2020 In this paper we establish a new half-discrete Hilbert-type inequality involving the variable upper limit integral and partial sums. As applications, an inequality obtained from the special case of the half-discrete Hilbert-type inequality is further ...
Jianquan Liao, Shanhe Wu, Bicheng Yang
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source