Results 61 to 70 of about 1,296,830 (230)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Monthly runoff prediction using modified CEEMD-based weighted integrated model
Journal of Water and Climate Change, 2021 Due to the nonlinear characteristics of runoff data and the poor performance of the single prediction model, a weighted integrated modified complementary ensemble empirical mode decomposition (MCEEMD)-based model was proposed to predict the monthly ...
Xinqing Yan +3 more
doaj +1 more source
Sintering characteristics and properties of PuS and PuP are determined [PDF]
, 1969 Report on the preparation of plutonium monosulphide and plutonium monophosphide includes a description of the sintering characteristics and properties of these high-temperature compounds.
Kruger, O. L., Moser, J. B.
core +1 more source
Nonvanishing and Central Critical Values of Twisted $L$-functions of Cusp Forms on Average [PDF]
, 2015 Let $f$ be a holomorphic cusp form of integral weight $k \geq 3$ for $\Gamma_{0}(N)$ with nebentypus character $\psi$. Generalising work of Kohnen and Raghuram we construct a kernel function for the $L$-function $L(f,\chi,s)$ of $f$ twisted by a ...
Schwagenscheidt, Markus
core +1 more source
A Head-Weighted Gap-Sensitive Correlation Coefficient [PDF]
Proceedings of the 38th International ACM SIGIR Conference on Research and Development in Information Retrieval, 2015 Information retrieval systems rank documents, and shared-task evaluations yield results that can be used to rank information retrieval systems. Comparing rankings in ways that can yield useful insights is thus an important capability. When making such comparisons, it is often useful to give greater weight to comparisons near the head of a ranked list ...
Ning Gao, Douglas Oard
openaire +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
, 2020 We introduce and study the category of modular (i.e. with coefficient of positive characteristic) monodromic perverse sheaves on complex stratified $T$-varieties, with $T$ a complex algebraic torus.
Gouttard, Valentin
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source