Results 81 to 90 of about 1,938,621 (298)

Nonvanishing and Central Critical Values of Twisted $L$-functions of Cusp Forms on Average [PDF]

open access: yes, 2015
Let $f$ be a holomorphic cusp form of integral weight $k \geq 3$ for $\Gamma_{0}(N)$ with nebentypus character $\psi$. Generalising work of Kohnen and Raghuram we construct a kernel function for the $L$-function $L(f,\chi,s)$ of $f$ twisted by a ...
Schwagenscheidt, Markus
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

A weighted transplantation theorem for Jacobi coefficients [PDF]

open access: yesJournal of Approximation Theory, 2019
We present a transplantation theorem for Jacobi coefficients in weighted spaces. In fact, by using a discrete vector-valued local Calderón-Zygmund theory, which has recently been furnished, we prove the boundedness of transplantation operators from $\ell^p(\mathbb{N},w)$ into itself, where $w$ is a weight in the discrete Muckenhoupt class $A_{p ...
Arenas, Alberto   +2 more
openaire   +5 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Study of the Mechanism of Antiemetic Effect of Lavandula angustifolia Mill. Essential Oil Based on Ca2+/CaMKII/ERK1/2 Pathway

open access: yesDrug Design, Development and Therapy, 2022
Jia Li,1,* Xiao Wang,1,* Shining Xun,2,* Qiuting Guo,3 Yao Wang,1 Yanzuo Jia,1 Wenfei Wang,1 Yujiao Wang,1 Taotao Li,1 Tiantian Tang,1 Junbo Zou,1 Mei Wang,1 Ming Yang,4 Fang Wang,4 Xiaofei Zhang,1,4 Changli Wang1 1Department of Pharmaceutics,
Li J   +15 more
doaj  

On a New Half-Discrete Hilbert-Type Inequality Involving the Variable Upper Limit Integral and Partial Sums

open access: yesMathematics, 2020
In this paper we establish a new half-discrete Hilbert-type inequality involving the variable upper limit integral and partial sums. As applications, an inequality obtained from the special case of the half-discrete Hilbert-type inequality is further ...
Jianquan Liao, Shanhe Wu, Bicheng Yang
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

On a New Extended Hardy–Hilbert’s Inequality with Parameters

open access: yesMathematics, 2020
In this paper, by introducing parameters and weight functions, with the help of the Euler−Maclaurin summation formula, we establish the extension of Hardy−Hilbert’s inequality and its equivalent forms.
Bicheng Yang, Shanhe Wu, Jianquan Liao
doaj   +1 more source

Interaction effects on prediction of children weight at school entry using model averaging [PDF]

open access: yes, 2018
Model selection introduce uncertainty to the model building process, therefore model averaging was introduced as an alternative to overcome the problem of underestimate of standards error in model selection.
Abdullah, Mohd Asrul Affendi   +2 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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