Results 81 to 90 of about 2,086,718 (267)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Journal of Inequalities and Applications, 2016 By applying the weight functions, the technique of real analysis and Hermite-Hadamard’s inequality, a half-discrete Hardy-Hilbert-type inequality related to the kernel of exponential function with the best possible constant factor expressed by the gamma ...
Jianquan Liao, Bicheng Yang
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A system-theory-based model for monthly river runoff forecasting: model calibration and optimization
Journal of Hydrology and Hydromechanics, 2014 River runoff is not only a crucial part of the global water cycle, but it is also an important source for hydropower and an essential element of water balance.
Wu Jianhua +3 more
doaj +1 more source
Demonstratio Mathematica, 2014 In this paper, we consider the Nemytskii operator (Hf)(t) = h(t, f(t)), generated by a given function h. It is shown that if H is globally Lipschitzian and maps the space of functions of bounded (p,2,α)-variation (with respect to a weight function α ...
Aziz Wadie
doaj +1 more source
Weighted Noncommutative Banach Function Spaces
, 2019 We review the concept of a weighted noncommutative Banach function space. This concept constitutes a generalisation of the by now well-known theory of noncommutative Banach function spaces associated with a semifinite von Neumann algebra. In this review we remind the reader of the quantum statistical problem which gave birth to this concept, we ...
Labuschagne, L.E., Steyn, C.
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Nauka ta progres transportu, 2014 Purpose. Development and substantiation of a new method of structural identification of electrical devices of electric traction systems for both DC and AC current. Methodology.
T. N. Mishchenko
doaj +1 more source