Results 161 to 170 of about 719,182 (313)

Pregnancy-associated breast cancer: gestational weight gain impact and nomogram validation. [PDF]

open access: yesBMC Cancer
Liu C   +9 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Gestational Weight Gain and Pregnancy Outcomes After GLP-1 Receptor Agonist Discontinuation. [PDF]

open access: yesJAMA
Maya J   +11 more
europepmc   +1 more source

Lowered weight gain during pregnancy and risk of neural tube defects among offspring [PDF]

open access: bronze, 2001
Gary M. Shaw   +4 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Association Between Gestational Weight Gain and Obstetric Anal Sphincter Injury. [PDF]

open access: yesO G Open
Khademioore S   +5 more
europepmc   +1 more source

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