Results 141 to 150 of about 166,174,665 (263)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Portrait of Lloyd Rees, 1983 [picture] /
, 1983 Title from label on back of print.; Part of the collection: Portraits of Australian artists 1968-1993.; Reference print at P641/6/R.; Also available online at: http://nla.gov.au/nla.pic ...
Weight, Greg, 1946-
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Portrait of Geoff de Groen, 2001 [picture] /
, 2001 Title supplied by vendor.; Part of collection: Portraits of six Australian artists.
Weight, Greg, 1946-
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
The Weight of Evidence for Diuretics and Parachutes
Journal of the American College of Cardiology, 2020 Zachary L, Cox, Lynne Warner, Stevenson
openaire +2 more sources
Portrait of John Wolseley, 2001 [picture] /
, 2001 Title supplied by vendor.; Part of collection: Portraits of six Australian artists. Portrait taken at John Wolseley's studio, Whipstick Forest, North Bendigo, Victoria, 20 March 2001.
Weight, Greg, 1946-
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Technology Evaluation Via Loss Management Models Formulated in Terms of Vehicle Weight
, 2000 Presented at the 59th International Conference on Mass Properties Engineering, St. Louis, June 5-7, 2000.Mass properties engineering is today an established field and an indispensable part of the design process.
Mavris, Dimitri N. +1 more
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source