Results 71 to 80 of about 92,089 (307)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Sistem Pendukung Keputusan Menggunakan Metode WASPAS Untuk Pemilihan Aplikasi Manajemen Bisnis dan Keuangan

Journal of Information and Technology
Dalam bisnis yang dinamis dan kompleks, manajemen efektif sangat penting, terutama dalam penggunaan aplikasi bisnis dan keuangan. Namun, banyaknya aplikasi yang tersedia membuat pemilihan aplikasi yang tepat menjadi rumit dan memakan waktu.
Idrus Ramadhan, Nurhasan Nugroho, Hadi Kurniawanto, Joni Warta   +3 more
doaj   +1 more source

Selecting the Best Waste Disposal Method in Health Using Combined Method of Fuzzy Analytical Hierarchy Process and Fuzzy Weighted Aggregated Sum Product Assessment

پیاورد سلامت, 2022
Background and Aim: Inattention of hospital waste management has caused many problems. As a consequence, it has put the environment and human health at serious risk.
Hamzeh Amin-Tahmasbi, Hossein Nasirzadeh
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Paradigm shift in implementing smart technologies for machinery optimisation in manufacturing using decision support system

Alexandria Engineering Journal
There is a revolution taking place in the industrial sector as a result of intelligent technologies that optimise machinery. In light of the requirements of the present day, the traditional methods are not going to suffice.
Li Ji, Dalei Zhang, Zhijia Wang, Mingling Liu, Meiling Sun, Hong Zhang, Naoufel Kraiem, Mohd Anjum   +7 more
doaj   +1 more source

Interactive Internet Framework Proposal of WASPAS Method: A Computational Contribution for Decision-Making Analysis

Mathematics, 2023
Concerning the development of computational tools and solutions as a decision-making aid, this paper presents the results of the waspasWEB project, which strives to provide decision-makers with a readily accessible mechanism to employ the weighted ...
Flavio Barbara, Marcos dos Santos, Antônio Sergio Silva, Miguel Ângelo Lellis Moreira, Luiz Paulo Fávero, Enderson Luiz Pereira Júnior, Wagner dos Anjos Carvalho, Fernando Martins Muradas, Daniel Augusto de Moura Pereira, Anderson Gonçalves Portella   +9 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Evaluation framework for urban sustainability assessment tools based on a decision-making approach

Ain Shams Engineering Journal
The availability of Urban Sustainability Assessment Tools (USATs) is considered essential in societies. Nevertheless, assessing USATs is challenging because inherent contradictions, compromises, and different tendencies characterise the models.
A.S. Albahri, Yahya Layth Khaleel, Mustafa Abdulfattah Habeeb, Reem D. Ismael, Qabas A. Hameed, O.S. Albahri, A.H. Alamoodi, Raad Z. Homod, Ghada A. Alsawah, Iman Mohamad Sharaf   +9 more
doaj   +1 more source

SISTEM PENDUKUNG KEPUTUSAN PENENTUAN RUMAH TANGGA MISKIN PADA DESA CIBANGKONG DENGAN METODE WASPAS

Jurnal Riset Informatika, 2019
In the current era, various business process activities require the application of information technology. Decision making is one of the business process activities that can be helped by the existence of technology. Determining poor families is a complex
Tuti Haryanti, Laela Kurniawati, Sugeng Riyadi   +2 more
doaj   +1 more source