Results 91 to 100 of about 631,044 (314)

Weighted Approximation for Jackson-Matsuoka Polynomials on the Sphere

open access: yesAbstract and Applied Analysis, 2012
We consider the best approximation by Jackson-Matsuoka polynomials in the weighted Lp space on the unit sphere of Rd. Using the relation between K-functionals and modulus of smoothness on the sphere, we obtain the direct and inverse estimate of ...
Guo Feng
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Degree of Monotone Approximation in , p Lα Spaces

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
The aim of this paper is to study the best approximation of unbounded functions in the weighted spaces , 1, 0 , p p L α α ≥>.
I. Z. Shamkhi, S. K. Jassim
doaj  

Low-rank matrix approximation with weights or missing data is NP-hard [PDF]

open access: yes
Weighted low-rank approximation (WLRA), a dimensionality reduction technique for data analysis, has been successfully used in several applications, such as in collaborative filtering to design recommender systems or in computer vision to recover ...
GILLIS, Nicolas, GLINEUR, François
core  

Approximation by weighted polynomials

open access: yesJournal of Approximation Theory, 2003
The paper is devoted to the study of approximation by weighted polynomials. The author proves that if \(xQ'(x)\) is increasing on \((0,\infty)\) and \(w(x)= \exp(-Q(x))\) is the corresponding weight on \([0,\infty)\), then every continuous function that vanishes outside.
openaire   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Global universal approximation of functional input maps on weighted spaces [PDF]

open access: green, 2023
Christa Cuchiero   +2 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Rational Approximation with Varying Weights, II

open access: yesJournal of Approximation Theory, 1996
This paper is a continuation of the first part published in [\textit{P. Borwein, E. A. Rakhmanov} and \textit{E. B. Saff}, Constructive Approximation 12, No. 2, 223-240 (1996; Zbl 0870.41010)]. Given \(\alpha >0\), \(\beta \geq 0\) and the varying weight \(\omega^n(x):= e^{nx}\), the authors prove that any real-valued function \(f \in C[0,a]\) is the ...
Rakhmanov, E.A, Saff, E.B, Simeonov, P.C
openaire   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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