Results 81 to 90 of about 1,126,452 (304)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

On the approximation of Kantorovich-type Szàsz-Charlier operators

Demonstratio Mathematica
In this study, we introduce the Kantorovich-type modified Szàsz-Charlier operators and examine their approximation properties within the framework of fractional modeling and control theory. These operators are defined using the Korovkin-type theorem, and
Karabıyık Ümit, Ayık Adem
doaj   +1 more source

Approximate weighted 3-coloring

CoRR
The paper considers the NP-hard graph vertex coloring problem, which differs from traditional problems in which it is required to color vertices with a given (or minimal) number of colors so that adjacent vertices have different colors. In the problem under consideration, a simple edge-weighted graph is given.
Adil I. Erzin, Roman V. Plotnikov, Georgii Zhukov   +2 more
openaire   +2 more sources

Approximating Steiner Networks with Node Weights [PDF]

SIAM Journal on Computing, 2008
The (undirected) Steiner Network problem is: given a graph G = (V, E) with edge/node weights and edge-connectivity requirements {r(u, v) : u, v ∈ U ⊆ V}, find a minimum weight subgraph H of G containing U so that the uv-edge-connectivity in H is at least r(u, v) for all u, v ∈ U.
openaire   +3 more sources

A linear approximation method for the Shapley value [PDF]

, 2008
The Shapley value is a key solution concept for coalitional games in general and voting games in particular. Its main advantage is that it provides a unique and fair solution, but its main drawback is the complexity of computing it (e.g for voting games ...
Fatima, Shaheen S, Jennings, Nicholas R., Jennings, Nicholas R, Fatima, Shaheen S., Wooldridge, Michael   +4 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Approximation Properties of Certain Summation Integral Type Operators

Demonstratio Mathematica, 2015
In the present paper, we study approximation properties of a family of linear positive operators and establish direct results, asymptotic formula, rate of convergence, weighted approximation theorem, inverse theorem and better approximation for this ...
Patel P., Mishra Vishnu Narayan
doaj   +1 more source

Algorithms and literate programs for weighted low-rank approximation with missing data

, 2011
Linear models identification from data with missing values is posed as a weighted low-rank approximation problem with weights related to the missing values equal to zero.
Markovsky, Ivan
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

New Characterization for Nonlinear Weighted Best Simultaneous Approximation

International Journal of Mathematics and Mathematical Sciences, 2009
This paper is concerned with the problem of a wide class of weighted best simultaneous approximation in normed linear spaces, and it establishes a new characterization result for the class of approximation by virtue of the notion of simultaneous regular ...
Xianfa Luo, Delin Wu, Jinsu He
doaj   +1 more source