Results 121 to 130 of about 4,239 (245)

Toxic mechanisms of amyloid oligomers and therapeutic strategies

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Amyloid oligomers are increasingly recognized as the major toxic contributors across protein‐misfolding disorders. In this review, we cover mechanistic evidence showing how these transient and structurally heterogeneous oligomers disrupt cellular homeostasis by: (i) permeabilizing lipid membranes and forming ion‐conducting pores; (ii ...
Magdalena I. Ivanova, Carmelo La Rosa, Ayyalusamy Ramamoorthy   +2 more
wiley   +1 more source

Assessing Refugee Trauma: Transformative Clinical Training in a Community Service‐Learning Model

Journal of Marital and Family Therapy, Volume 52, Issue 2, April 2026.
ABSTRACT Marriage and family therapy emphasizes systemic responsiveness, yet integrating advocacy into clinical training remains limited. This pilot study examines a trauma‐informed service‐learning partnership with a community‐based organization, where graduate students conducted supervised forensic evaluations for asylum seekers.
Hans Reihling, Nadia Rojas Jones, Erica Nager, Marissa Lopez Juarez   +3 more
wiley   +1 more source

Introduction: The (Im)material Spectrum of Manuscript and Print Interaction☆

Renaissance Studies, Volume 40, Issue 2, Page 148-165, April 2026.
Abstract This introductory essay to the special issue on Early Modern English Textual Cultures Between Manuscript and Print first outlines previous research into different kinds of interaction between manuscript and print. Examples of this interplay include, for instance, the transmission of text and images from one medium into another, the use of ...
Sara Norja, Mari‐Liisa Varila
wiley   +1 more source

Comparative analysis of pomological and phytochemical characteristics in white‐ and red‐fleshed pitaya (Hylocereus spp.), with molecular docking insights into key bioactive compounds

Journal of the Science of Food and Agriculture, Volume 106, Issue 4, Page 2200-2210, 15 March 2026.
Abstract BACKGROUND Cacti, including pitaya (Hylocereus spp.), are rich in antioxidants that will undoubtedly gain importance under ongoing climate change as water resources decline. Yet the molecular basis linking composition to antioxidant function remains incompletely defined. We compared white‐fleshed H. undatus and red‐fleshed H. polyrhizus across
Kerem Mertoglu, Annik Fischer, Sina Zargarchi, Melekber Sulusoglu Durul, Magdalena Köpsel, Erdi Can Aytar, Ibrahim Bulduk, Barıs Kaki, Tuba Esatbeyoglu   +8 more
wiley   +1 more source

Inner‐Layer Asymptotics in Partially Perforated Domains: Coupling Across Flat and Oscillating Interfaces

Mathematical Methods in the Applied Sciences, Volume 49, Issue 4, Page 3353-3384, 15 March 2026.
ABSTRACT The article examines a boundary‐value problem in a bounded domain Ωε$$ {\Omega}_{\varepsilon } $$ consisting of perforated and imperforate regions, with Neumann conditions prescribed at the boundaries of the perforations. Assuming the porous medium has symmetric, periodic structure with a small period ε$$ \varepsilon $$, we analyze the limit ...
Taras Melnyk
wiley   +1 more source

Widespread invasion of a giant prolactinoma via valveless venous channels: illustrative case. [PDF]

J Neurosurg Case Lessons
Liang AS, Nadel JL, de Lotbiniere-Bassett M, Salzman KL, Couldwell WT.   +4 more
europepmc   +1 more source

Diversification with minor oilseeds: Effects on system productivity and nitrogen use efficiency in semi‐arid Canadian prairies

Agronomy Journal, Volume 118, Issue 2, March/April 2026.
Abstract Diversified cropping systems in the semi‐arid Canadian prairies comprise major cereal, oilseed, and pulse crops. Further diversification with minor oilseeds, such as oriental (Brassica juncea), industrial (Brassica carinata L.), and yellow (Sinapis alba L.) mustard, camelina [Camelina sativa (L.) Crantz], and flax (Linum usitatissimum L ...
Shayeb Shahariar, Mervin St. Luce, Manjula Bandara, Charles M. Geddes, Kui Liu, Prabhath Lokuruge, Mohammad Khakbazan, Brian McConkey   +7 more
wiley   +1 more source

Discrete stochastic maximal regularity. [PDF]

Math Ann
Evangelopoulos-Ntemiris F, Veraar M.
europepmc   +1 more source

APOE and plasma AD biomarkers: The role of genetic ancestry in Hispanics/Latinos

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract BACKGROUND Apolipoprotein E (APOE) alleles are well‐established genetic risk factors for Alzheimer's disease (AD), but their effects on AD biomarkers (amyloid beta [Aβ]42/40, phosphorylated tau [p‐tau]181, neurofilament light chain [NfL], and glial fibrillary acidic protein [GFAP]) may vary across populations due to ancestry‐, age‐, and sex ...
Caitlin Cheung, Natasha Z. Anita, Paola Filigrana, Myriam Fornage, Kevin A. Gonzalez, Linda C. Gallo, Carmen R. Isasi, Robert C. Kaplan, Xihao Li, Freddie Márquez, Humberto Parada Jr., Krista M. Perreira, Alberto R. Ramos, Tatjana Rundek, Wassim Tarraf, Fernando D. Testai, Charles DeCarli, Hector M. González, Tamar Sofer   +18 more
wiley   +1 more source

PHASE: Personalized Head-based Automatic Simulation for Electromagnetic properties in 7T MRI. [PDF]

Magn Reson Imaging
Lu Z, Liang H, Lu M, Martin D, Hardy BM, Dawant BM, Wang X, Yan X, Huo Y.   +8 more
europepmc   +1 more source