Results 61 to 70 of about 2,169,038 (282)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Self-adaption image weighted mean filter design based on FPGA

open access: yesDianzi Jishu Yingyong, 2019
In order to solve the problem of noise preprocessing in the process of image acquisition by complementary metal oxide semiconductor(CMOS) image sensor, a configurable adaptive weighted mean filter module in FPGA is proposed.
Wu Haonan   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Projected shrinking of tropical vegetation biomass potential with future hydroclimatic shifts

open access: yesEnvironmental Research Letters
Global change threatens the carbon stocks stored in tropical ecosystems. However, considerable uncertainty remains regarding the estimates of these future carbon losses.
Félicien Meunier   +7 more
doaj   +1 more source

Universal approximation by regular weighted means [PDF]

open access: yesPacific Journal of Mathematics, 1985
In this paper we shall improve upon the results by \textit{K. Faulstich}, \textit{W. Luh} and \textit{L. Tomm} [Manuscr. Math. 36, 309-321 (1981; Zbl 0479.30023)] by (i) considering power series representing other meromorphic functions f, (ii) using a regular weighted means method D to obtain the overconvergence property and (iii) showing that D has a ...
Thorpe, B., Tomm, L.
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Some weighted operator geometric mean inequalities

open access: yesپژوهش‌های ریاضی, 2017
In this paper, using the extended Holder- -McCarthy inequality, several inequalities involving the α-weighted geometric mean ...
Alemeh Sheikhhosseini   +2 more
doaj  

weighted mean

open access: yes, 2014
Citation: 'weighted mean' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.W06670 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
openaire   +1 more source

Notes on Weighted Mean and Median [PDF]

open access: yesTamap Journal of Mathematics and Statistics, 2018
The paper investigates the application and generalization of the weighted mean and median by using continuous and convex functions. The paper offers a clear and systematic approach to the notion of weighted medians. As a result, essential characteristics of weighted medians are presented better.
Pavić, Zlatko, Novoselac, Vedran
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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