Results 41 to 50 of about 8,094,665 (258)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

The effect of data sources on calculating mean temperature and integrated water vapor in Iran

Meteorological Applications, 2023
The weighted mean temperature (Tm) plays a crucial role in calculating Precipitable Water Vapor (PWV) and integrated water vapor (IWV) using Global Navigation Satellite Systems (GNSS) techniques.
Hassan Rahimi, Jamal Asgari, Vahab Nafisi   +2 more
doaj   +1 more source

Fundamental Study of Weighting Factors for Calculating Mean Skin Temperature

Journal of the Human-Environment System, 2006
It was proposed to calculate a formula for mean skin temperature weighted with both the heat transfer coefficient and skin surface area ratios. Calculating the mean skin temperature based on the heat balance equation between the human body and the environment yielded the formula with the weighting factor including not only the skin surface area ratio ...
Kuwabara, Kouhei, Mochida, Tohru, Nagano, Katsunori, Shimakura, Kazumi   +3 more
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

An ERA5-Based Hourly Global Pressure and Temperature (HGPT) Model

Remote Sensing, 2020
The Global Navigation Satellite System (GNSS) meteorology contribution to the comprehension of the Earth’s atmosphere’s global and regional variations is essential.
Pedro Mateus, João Catalão, Virgílio B. Mendes, Giovanni Nico   +3 more
doaj   +1 more source

A Novel Global Grid Model for Atmospheric Weighted Mean Temperature in Real-Time GNSS Precipitable Water Vapor Sounding

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2023
The atmospheric weighted mean temperature (Tm) is an important parameter in calculating the precipitable water vapor from Global Navigation Satellite System (GNSS) signals. As both GNSS positioning and GNSS precipitable water vapor detection require high
Liangke Huang, Zhedong Liu, Hua Peng, Si Xiong, Ge Zhu, Fade Chen, Lilong Liu, Hongchang He   +7 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Atmospheric Water Vapor Monitoring on Horseshoe Island, Antarctica: GNSS Observations at the Permanent TUR1 and TUR2 Stations Using a Regional Tm Calibration

Remote Sensing
Atmospheric water vapor plays a critical role in the climate system, governing energy balance, climate variability and precipitation processes. Accurate monitoring of precipitable water vapor (PWV) is therefore essential for both meteorological and ...
Mahmut Oğuz Selbesoğlu, Görkem Yalçın, Mustafa Fahri Karabulut, Hasan Hakan Yavaşoğlu, Esra Günaydın, Vahap Engin Gülal   +5 more
doaj   +1 more source

Improved Empirical Coefficients for Estimating Water Vapor Weighted Mean Temperature over Europe for GNSS Applications

Remote Sensing, 2019
Development of the so-called global navigation satellite system (GNSS) meteorology is based on the possibility of determining a precipitable water vapor (PWV) from a GNSS zenith wet delay (ZWD).
Zofia Baldysz, Grzegorz Nykiel
doaj   +1 more source