Results 71 to 80 of about 1,699,857 (244)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

The fractional integral between weighted Orlicz and $BMO_{\phi}$ spaces on spaces of homogeneous type [PDF]

open access: yes, 2003
summary:In this work we give sufficient and necessary conditions for the boundedness of the fractional integral operator acting between weighted Orlicz spaces and suitable $BMO_{\phi}$ spaces, in the general setting of spaces of homogeneous type.
Pradolini, Gladis, Salinas, Oscar
core  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

On a general class of q-rational type operators [PDF]

open access: yesMathematica Moravica, 2015
In this study, we define a general class of rational type operators based on q-calculus and investigate the weighted approximation properties of these operators by using A-statistical convergence.
Ispir Nurhayat
doaj  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Convolution operators and the discrete Laplacian [PDF]

open access: yes, 2009
PhDIn this thesis, we obtain new results for convolution operators on homogeneous spaces and give applications to the Laplacian on a homogeneous graph. Some of these results have been published in joint papers [13, 14] with my supervisor.
Chen, Chung-Chuan
core   +2 more sources

Order-Bounded Difference in Weighted Composition Operators Between Fock Spaces

open access: yesMathematics
There are two aims in this paper. The first aim is to characterize the order-bounded weighted composition operators between Fock spaces, and the second is to further characterize the order-bounded difference in weighted composition operators between Fock
Xiao-Feng Peng, Zhi-Jie Jiang
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Commutators for the maximal and sharp functions with weighted Lipschitz functions on weighted Morrey spaces

open access: yesDemonstratio Mathematica
We study the boundedness of commutators of the Hardy-Littlewood maximal function and the sharp maximal function on weighted Morrey spaces when the symbols of the commutators belong to weighted Lipschitz spaces (weighted Morrey-Campanato spaces). Some new
Zhang Pu, Fan Di
doaj   +1 more source

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