FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Complete convergence and complete moment convergence for randomly weighted sums of martingale difference sequence. [PDF]
J Inequal Appl, 2018 Ma H, Sun Y.
europepmc +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
On the strong convergence for weighted sums of negatively superadditive dependent random variables. [PDF]
J Inequal Appl, 2017 Meng B, Wang D, Wu Q.
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Large Deviation Probabilities for Weighted Sums
The Annals of Mathematical Statistics, 1972 Taking as our point of departure the methods and results in a 1960 paper of Bahadur and Ranga Rao, we derive asymptotic representations of large deviation probabilities for weighted sums of independent, identically distributed random variables. The main theorem generalizes the Bahadur-Ranga Rao result in the absolutely continuous case.
openaire +3 more sources
Complete convergence and complete moment convergence for weighted sums of extended negatively dependent random variables under sub-linear expectation. [PDF]
J Inequal Appl, 2017 Zhong H, Wu Q.
europepmc +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
On the exponential inequality for weighted sums of a class of linearly negative quadrant dependent random variables. [PDF]
ScientificWorldJournal, 2014 Xing G, Yang S.
europepmc +1 more source
Strong laws for weighted sums of i.i.d. random variables
Strong laws of large numbers are established for the weighted sums of i.i.d. random variables which have higher-order moment condition. One of the results of Bai and Cheng (2000, Statist. Probab. Lett.
Sung, Soo Hak
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