Results 91 to 100 of about 21,411 (263)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Strong uniform laws of large numbers for bootstrap means and other randomly weighted sums
, 2023 This article establishes novel strong uniform laws of large numbers for randomly weighted sums such as bootstrap means. By leveraging recent advances, these results extend previous work in their general applicability to a wide range of weighting ...
Miller, Jeffrey W., Spencer, Neil A.
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Control Charts Based on Weighted Sums
The Annals of Statistics, 1974 In a continuous production process, samples of fixed size are taken at regular intervals of time and a statistic $X_n$ is computed from the $n$th sample, $n = 1,2, \cdots$. In this paper, we study process inspection schemes which stop the production and take corrective action with $N = \text{first} n \geqq 1$ such that $\sum^n_{i=1} c_{n-i} X_i \geqq h$
openaire +3 more sources
Complete Convergence and Some Maximal Inequalities for Weighted Sums of Random Variables [PDF]
, 2007 Let be a sequence of arbitrary random variables with and , for every and be an array of real numbers. We will obtain two maximal inequalities for partial sums and weighted sums of random variables and also, we will prove complete convergence for ...
M. Amini
core
Confidence intervals for weighted sums of poisson parameters
, 1991 Directly standardized mortality rates are examples of weighted sums of Poisson rate parameters. If the numbers of events are large then normal approximations can be used to calculate confidence intervals, but these are inadequate if the numbers are small.
Dobson AJ +11 more
core +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
On weighted Lebesgue function type sums
Journal of Approximation Theory, 2007 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources