Results 81 to 90 of about 21,411 (263)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Sum and Weighted Sum Formulas for Fibonacci and Lucas Quaternions
Aksaray University Journal of Science and EngineeringFibonacci and Lucas quaternions are deeply studied in the literature after its definition by Horadam in 1963. Binet formula, generation function, Cassini, Catalan, Honsberger, and other identities for these sequences studied in different quaternion algebra types like split quaternion algebra, dual quaternion algebra, etc.
openaire +3 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Weighted and Self-normalized Sums in Free Probability Theory
Neufeld L. Weighted and Self-normalized Sums in Free Probability Theory. Bielefeld: Universität Bielefeld; 2025.In this thesis we study the asymptotic behavior of weighted and self-normalized sums in free probability theory and determine the ...
Neufeld, Leonie
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Small deviation probabilities of weighted sums with fast decreasing weights
, 2015 We examine small deviation probabilities of weighted sums of i.i.d. positive random variables whose distribution function is regularly varying at zero provided that weights are decreasing fast enough.We examine small deviation probabilities of weighted
Rozovsky, Leonid V.
core
Complete Convergence for Weighted Sums of ρ∗-Mixing Random Variables
, 2010 We obtain the complete convergence for weighted sums of ρ∗-mixing random variables. Our result extends the result of Peligrad and Gut (1999) on unweighted average to a weighted average under a mild condition of weights.
Soo Hak Sung
core +1 more source