Results 121 to 130 of about 211,923 (289)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
On sums of weighted averages of $\gcd$-sum functions
, 2018 Let $\gcd(j,k)$ be the greatest common divisor of the integers $j$ and $k$. In this paper, we give several interesting asymptotic formulas for weighted averages of the $\gcd$-sum function $f(\gcd(j,k)) $ and the function $\sum_{d|k, d^{s}|j}(f* )(d) $ for any positive integers $j$ and $k$, namely $$ \sum_{k\leq x}\frac{1}{k^{r+1}}\sum_{j=1}^{k}j^{r}f(\
Kiuchi, Isao, Eddin, Sumaia Saad
openaire +2 more sources
Limit theorems for weighted Bernoulli random fields under Hannan's condition
, 2015 Consider a Bernoulli random field satisfying the Hannan's condition. Recently, invariance principles for partial sums of random fields over rectangular index sets are established.
Klicnarová, Jana +2 more
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Complete Convergence for Weighted Sums of Sequences of Negatively Dependent Random Variables
Journal of Probability and Statistics, 2011 Applying to the moment inequality of negatively dependent random variables the complete convergence for weighted sums of sequences of negatively dependent random variables is discussed.
Qunying Wu
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
On Complete Convergence for Weighted Sums of φ-Mixing Random Variables
Journal of Inequalities and Applications, 2010 Some results on complete convergence for weighted sums ∑i=1naniXi are presented, where {Xn, n≥1} is a sequence of φ-mixing random variables and {ani,n≥1,i≥1} is an array of constants.
Wang Xuejun +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Cylindric Reverse Plane Partitions and 2D TQFT
, 2018 The ring of symmetric functions carries the structure of a Hopf algebra. When computing the coproduct of complete symmetric functions $h_\lambda$ one arrives at weighted sums over reverse plane partitions (RPP) involving binomial coefficients.
Korff, Christian, Palazzo, David
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