Results 91 to 100 of about 451,044 (311)
تاثیر مدل وزن دهی و نمره کل سازی سوابق تحصیلی بر کارایی گزینش داوطلبان ورود به دانشگاه ها و مراکز آموزش عالی کشور [PDF]
پژوهش در نظامهای آموزشی, 2018 Objective: The purpose of this study was to identify the weight of each of the courses of academic record and scoring based on the psychometric approaches of factor analysis and the continuous IRT model and the approaches based on the viewpoint of the ...
Meysam Sadeghi +4 more
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Data-driven weights and restrictions in the construction of composite indicators
Croatian Operational Research Review, 2015 Composite indicators are increasingly recognized as a useful tool in policy analysis and public communication. However, if poorly constructed, they can send misleading policy messages.
Ana Perišić
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Weighted means and weighting functions
Kybernetika, 2006 Summary: We present some properties of mixture and generalized mixture operators with special stress on their monotonicity. We introduce new sufficient conditions for weighting functions to ensure the monotonicity of the corresponding operators. However, mixture operators, generalized mixture operators neither quasi-arithmetic means weighted by a ...
Mesiar, R. (Radko), Špirková, J.
openaire +3 more sources
Jurnal Ilmiah Computer ScienceThe best sales performance is one of the key elements in the business world that not only reflects the ability of individuals or sales teams to achieve sales targets, but also becomes a key pillar in the growth and success of the company.
Puspa Citra +2 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Weighting of items in a tutorial performance evaluation instrument: Statistical analysis and results
Health SA Gesondheid: Journal of Interdisciplinary Health Sciences, 2009 Weighting of items in an evaluation instrument contributes to more meaningful and valid interpretations of student performance in respect of each learning outcome or item being assessed.
Melanie L. Lack +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source