Results 101 to 110 of about 451,044 (311)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Weighted cages

open access: yesDiscrete Applied Mathematics
Cages ($r$-regular graphs of girth $g$ and minimum order) and their variants have been studied for over seventy years. Here we propose a new variant, "weighted cages". We characterize their existence; for cases $g=3,4$ we determine their order; we give Moore-like bounds and present some computational results.
Gabriela Araujo-Pardo   +3 more
openaire   +2 more sources

Hybrid Similarity Measure in SmartLP: A Case Based System in Lesson Planning

open access: yesJournal of ICT in Education, 2019
Planning for teaching imposes a significant burden on teachers as they need to prepare different lesson plans for different classes according to various constraints such as students’ ability and previous knowledge.
Aslina Saad   +2 more
doaj  

Loss-Balanced Task Weighting to Reduce Negative Transfer in Multi-Task Learning

open access: yesAAAI Conference on Artificial Intelligence, 2019
In settings with related prediction tasks, integrated multi-task learning models can often improve performance relative to independent single-task models.
Shengchao Liu, Yingyu Liang, A. Gitter
semanticscholar   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

BODY WEIGHT AND ORGAN WEIGHT IN RATS

open access: yesThe KITAKANTO Medical Journal, 1962
To define the standard for the normal physiological status of rats, about 300 Wistar strain rats, bred in our department, were examined for body weight gain with age in day, and weight of 11 organs-hypophysis, thyroid, adrenal, thymus, testis, ovary, uterus, heart, liver, spleen and kidney-were obtained for each body weight group.
Tadokoro, Sakutaro   +4 more
openaire   +3 more sources

Estimativas obtidas de um levantamento complexo

open access: yesRevista de Saúde Pública
OBJETIVO: Avaliar o impacto do plano de amostragem e o efeito da ponderação, em dados provenientes da "Pesquisa Nacional sobre Demografia e Saúde" (PNDS-96).
Maria Helena de Sousa   +1 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Weight distribution of the crown-weight space

open access: yesEuropean Journal of Combinatorics, 2007
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Dae San Kim, Sung Hee Cho
openaire   +1 more source

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