Results 171 to 180 of about 1,205 (217)

<i>Thymus ad astra</i>, or spaceflight-induced thymic involution. [PDF]

Front Immunol
Muramatsu W, Maryanovich M, Akiyama T, Karagiannis GS.   +3 more
europepmc   +1 more source

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Exercise response to simulated weightlessness

Acta Astronautica, 1979
Two bed rest analog studies of space flight were performed; one 14 d and the other 28 d in duration. Exercise response was studied in detail during the 28 d study and following both the 14 d and 28 d studies. This paper relates the results of these studies to physiologic changes noted during and following space flight.
C F, Sawin, J A, Rummel, M C, Buderer
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Simulated Weightlessness Induces Hippocampal Insulin Resistance and Cognitive Impairment

Life Sciences, 2023
Growing evidence highlights the potential consequences of long-term spaceflight, including gray matter volume reduction and cognitive dysfunction with subclinical manifestations of diabetes mellitus among astronauts, but the underlying mechanisms remain unknown. In this study, we found that long-term simulated weightlessness induced hippocampal insulin
Jiahui, Li, Caiyan, Xue, Hongyan, Yang, Jiaxin, Zhang, Guohua, Li, Jijun, Li, Fang, Kuang, Jing, Chen, Shu, Zhang, Feng, Gao, Zhenzhen, Kou, Xing, Zhang, Ling, Dong   +12 more
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Correlation of macro and micro cardiovascular function during weightlessness and simulated weightlessness

Acta Astronautica, 1988
The investigation of cardiovascular function necessarily involves a consideration of the exchange of substances at the capillary. If cardiovascular function is compromised or in any way altered during exposure to zero gravity in space, then it stands to reason that microvascular function is also modified.
P M, Hutchins, T H, Marshburn, T L, Smith, S W, Osborne, C D, Lynch, S J, Moultsby   +5 more
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An upper arm model for simulated weightlessness

Acta Physiologica Scandinavica, 2000
This investigation examined the effects of 4 weeks of non‐dominant arm unloading on the functional and structural characteristics of the triceps brachii muscle of six normo‐active college‐age males (age: 23 ± 1 years, height: 176 ± 4 cm, weight: 76 ± 6 kg).
A C, Parcell, S W, Trappe, M P, Godard, D L, Williamson, W J, Fink, D L, Costill   +5 more
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Effects of muscle electrostimulation during simulated weightlessness

Acta Astronautica, 1975
In a 45-day experiment test subjects were exposed to bed rest with their heads down at -4 degrees C. Twice a day their muscles of the stomach, back, femur, and shin were stimulated with electric current for 25-30 min. The value of muscle tension was close to their maximum voluntary contraction.
L I, Kakurin, B B, Yegorov, Y I, Il'ina, M A, Cherepakhin   +3 more
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Decision making after 50 days of simulated weightlessness

Brain Research, 2009
By restricting physical activity levels, the bed rest simulation of weightlessness could be associated with changes in prefrontal cortex functioning that manifest as cognitive decrements, particularly for executive cognitive functions. We aimed to determine if performance on an executive function task was indeed affected by bed rest.
Darren M, Lipnicki, Hanns-Christian, Gunga, Daniel L, Belavy, Dieter, Felsenberg   +3 more
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The Effects of Simulated Weightlessness on Bone Maturation*

Endocrinology, 1987
In earlier studies we showed that elevating the hind limbs of growing rats for up to 2 weeks results in a temporary cessation of bone growth in the hind limbs and a transient fall in the serum levels of 1,25-dihydroxyvitamin D. To determine whether such skeletal unloading also retards the maturation of bone, as seen in vitamin D-deprived animals, we ...
D D, Bikle, B P, Halloran, C M, Cone, R K, Globus, E, Morey-Holton   +4 more
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Changes of brain response induced by simulated weightlessness

Acta Astronautica, 1992
The characteristics change of brain response was studied during 15 degrees head-down tilt (HDT) comparing with 45 degrees head-up tilt (HUT). The brain responses evaluated included the EEG power spectra change at rest and during mental arithmetic, and the event-related potentials (ERPs) of somatosensory, selective attention and mental arithmetic ...
J, Wei, G, Yan, Z, Guan
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Skeletal abnormalities in rats induced by simulated weightlessness

Metabolic Bone Disease and Related Research, 1982
A hypokinetic model has been developed which attempts to simulate the weightlessness experienced during space flight. Male rats (approximately 130 g) were suspended from the model with a head-down tilt for a two-week period. Total mechanical unloading of the hind limbs and partial unloading of the fore limbs occurred.
T J, Wronski, E R, Morey
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