Results 111 to 120 of about 3,527,904 (336)

Refah Devleti Anlayışının Belediyelere Yansıması: Ankara Pursaklar Belediyesi Örneği

Ekonomi, Politika & Finans Araştırmaları Dergisi, 2017
İkinci dünya savaşı sonrası dünyada yükselen refah devleti kavramının küreselleşme ile yayılması ile birlikte ortaya çıkan sosyal belediyecilik uygulamaları makalenin konusunu oluşturmaktadır.
Murat Ezer
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Comparison of the Happiness Level of Farmers at Suburban Villages with Farmers at Remotes Villages [PDF]

BIO Web of Conferences
The study aims to analyze the level of happiness of farmers at two villages The research was conducted at X village, Pare sub-district, Kediri Regency (a suburban village), and Y village, Ngancar district, Kediri Regency (a village far from the city ...
Ibrahim Jabal Tarik, Mufriantie Fithri, Amir Nur Ocvanny, Hariyady Hariyady, Fauzi Kamarudin Mohammad   +4 more
doaj   +1 more source

Punishing the Poor Through Welfare Reform: Cruel and Unusual? [PDF]

, 2015
This Comment aims to show how the Eighth Amendment intersects with welfare reform and what constitutional limits exist vis-à-vis welfare restrictions for society’s neediest citizens.
Kendrex, Jennifer E.K.
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Constructions of welfare recipients and work in New Zealand newspapers : an examination of discourse and policy : a thesis presented in fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University, New Zealand [PDF]

, 2016
This paper drew from discursive psychology and Foucauldian discourse analysis to analyse and critique constructions of welfare, its recipients and proposed policies as they were discussed in 200 New Zealand newspaper accounts published between 2005 and ...
Wilson, Kimberly Rose
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

The Effect of Internal Marketing on the Prosperity of Maqashid Syariah Perspective Employees on Banking in Surakarta

Journal of Islamic Economic Laws
This study aims to determine the effect of internal marketing consisting of the dimensions of the Company Mission and Development of Human Resources on the welfare of employees from the perspective of Maqashid Syariah on banking in the city of Surakarta.
Raisa Aribatul Hamidah, Atika Fikri Tsani   +1 more
doaj   +1 more source