Results 121 to 130 of about 3,527,904 (336)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Evaluating Electricity Demand Elasticity From a Social Perspective: Implications for Sustainable Development and Urban Resilience

IEEE Access
The central focus of this study revolves around constructing a comprehensive load model to estimate the elasticity of electricity demand predicated on customers’ risk-averse tendencies.
Yaser A. Nanehkaran, Shixi Tang, Amir Bairami Akhi Jahani, Amir Niromandfam, Tolga Pusatli   +4 more
doaj   +1 more source

Farm-Animal Welfare, Legislation, and Trade [PDF]

, 2007
The US has among the weakest farm-animal-welfare standards in the developed world. Although improvements in farm-animal welfare are economically feasible, nations and states enacting protective regulation are threatened by competition with cheaper, non ...
Leahy, Cheryl, Matheny, Gaverick
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Italians Can Resist Everything, Except Flat-Faced Dogs!

Animals
Brachycephalic dogs remain highly popular despite the well-documented health problems associated with their conformation. The aim of this study was to investigate differences in the bonding between humans and dogs, behavioral characteristics, awareness ...
Simona Cannas, Clara Palestrini, Sara Boero, Alice Garegnani, Silvia M. Mazzola, Emanuela Prato-Previde, Greta V. Berteselli   +6 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Pilot Study: Simultaneous Daily Recording of Total Locomotor Activity and Heart Rate in Horses for Application in Precision Livestock Farming

Animals
Among physiological parameters, total locomotor activity (TLA) and heart rate (HR) are used as physiological indicators in animal welfare evaluations.
Francesca Aragona, Maria Rizzo, Federica Arrigo, Francesca Arfuso, Francesco Fazio, Elisabetta Giudice, Pietro Pugliatti, Giuseppe Piccione, Claudia Giannetto   +8 more
doaj   +1 more source

Welfare [PDF]

The American Historical Review, 1996
openaire   +2 more sources

Blue whales and seismic surveying in Australia [PDF]

Blue whale populations were devastated in the last century by commercial whaling, which reduced blue whales from a quarter of a million to just a few hundred animals. Australian waters are home to both the Antarctic blue whale and a smaller sub- species,
International Fund for Animal Welfare (IFAW)
core