Results 91 to 100 of about 1,159,902 (301)
Italian Journal of Animal Science, 2020 The present study aims to evaluate beef cattle welfare with an integrated approach as housing conditions and management practices change and to investigate the relationship between the adopted parameters and their applicability.
Martina Tarantola +13 more
doaj +1 more source
Peer mentorship and positive effects on student mentor and mentee retention and academic success [PDF]
, 2012 This study examined how the introduction of peer mentorship in an undergraduate health and social welfare programme at a large northern university affected student learning.
A. Bandura +23 more
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Silicon Valley versus Corporate Welfare [PDF]
, 1998 The estimated $65 billion a year that the federal government now spends on corporate welfare programs harms U.S. industry in general and Silicon Valley companies in particular.
T. J. Rodgers
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Animals, 2019 The aim of the study was to evaluate the welfare of dairy goats of 32 farms located in Northwestern Italy, applying an on-farm assessment protocol, centered on animal-, resources- and management-based measures.
Francesco Tiezzi +4 more
doaj +1 more source
Incorporation of conventional animal welfare assessment techniques into organic certification and farming [PDF]
, 2004 Providing assurances to consumers on the adherence to certain animal welfare-related standards is an important element of organic and farm assurance schemes.
Leeb, Christine +2 more
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source