Results 51 to 60 of about 15,623,747 (237)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Well Spacing Optimization for Tight Sandstone Gas Reservoir

open access: yes, 2010
In the past five years, tight sandstone gas reserves amounted to almost 50% of the newly proved natural gas reserves of PetroChina Co., Ltd. and will be one of the main targets of natural gas production for a long term.Means to determine the reasonable ...
Jianlin Guo   +4 more
core   +1 more source

Optimization of Well Spacing Ratio of Injection Production Wells in Low Permeability Anisotropic Reservoir [PDF]

open access: yes, 2016
According to the characteristics of anisotropy existed during the development of low permeability reservoirs, Shengli oilfield in Niu 20 reservoir as an example, by using reservoir numerical simulation method, considering the existing well pattern in low
LONG, Long   +3 more
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Investigation of the Effect of Natural Fractures on Multiple Shale-Gas Well Performance Using Non-Intrusive EDFM Technology

open access: yesEnergies, 2019
The influence of complex natural fractures on multiple shale-gas well performance with varying well spacing is poorly understood. It is difficult to apply the traditional local grid refinement with structured or unstructured gridding techniques to ...
Wei Yu   +3 more
doaj   +1 more source

Cluster Spacing Optimization for Horizontal-Well Fracturing in Shale Gas Reservoirs: Modeling and Field Application

open access: yes, 2018
Multi-stage fracturing in horizontal well is the core technology for commercial exploitation of shale gas reservoir, in which the cluster spacing plays an important role to impact the fracturing performance—undersized cluster spacing might make the ...
Ran Lin, Lan Ren, Jinzhou Zhao
core   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Research and application of well location deployment parameters for cluster development of medium-deep hydrothermal geothermal resources: A case study of HTC geothermal field [PDF]

open access: yesYouqicang pingjia yu kaifa
Under the framework of the national “double carbon” strategy, the efficient development and utilization of clean energy have become a focal point across various industries.
GAI Changcheng,ZHAO Zhongxin,REN Lu,YAN Yican,HOU Benfeng
doaj   +3 more sources

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