Results 51 to 60 of about 15,623,747 (237)
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Well Spacing Optimization for Tight Sandstone Gas Reservoir
In the past five years, tight sandstone gas reserves amounted to almost 50% of the newly proved natural gas reserves of PetroChina Co., Ltd. and will be one of the main targets of natural gas production for a long term.Means to determine the reasonable ...
Jianlin Guo +4 more
core +1 more source
Optimization of Well Spacing Ratio of Injection Production Wells in Low Permeability Anisotropic Reservoir [PDF]
According to the characteristics of anisotropy existed during the development of low permeability reservoirs, Shengli oilfield in Niu 20 reservoir as an example, by using reservoir numerical simulation method, considering the existing well pattern in low
LONG, Long +3 more
core +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
The influence of complex natural fractures on multiple shale-gas well performance with varying well spacing is poorly understood. It is difficult to apply the traditional local grid refinement with structured or unstructured gridding techniques to ...
Wei Yu +3 more
doaj +1 more source
Multi-stage fracturing in horizontal well is the core technology for commercial exploitation of shale gas reservoir, in which the cluster spacing plays an important role to impact the fracturing performance—undersized cluster spacing might make the ...
Ran Lin, Lan Ren, Jinzhou Zhao
core +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Research and application of well location deployment parameters for cluster development of medium-deep hydrothermal geothermal resources: A case study of HTC geothermal field [PDF]
Under the framework of the national “double carbon” strategy, the efficient development and utilization of clean energy have become a focal point across various industries.
GAI Changcheng,ZHAO Zhongxin,REN Lu,YAN Yican,HOU Benfeng
doaj +3 more sources

