Results 111 to 120 of about 2,574,835 (312)

Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions. [PDF]

open access: yes, 2018
Metazoan development depends on tightly regulated gene expression programs that instruct progenitor cells to adopt specialized fates. Recent work found that posttranslational modifications, such as monoubiquitylation, can determine cell fate also ...
Baur, Regina   +4 more
core  

Achievable rates for the Gaussian quantum channel [PDF]

open access: yes, 2001
We study the properties of quantum stabilizer codes that embed a finite-dimensional protected code space in an infinite-dimensional Hilbert space. The stabilizer group of such a code is associated with a symplectically integral lattice in the phase space
A. Steane   +25 more
core   +2 more sources

Understanding the rationale for metronidazole use in dogs and cats

open access: yesJournal of Small Animal Practice, EarlyView.
Objective It is currently unknown how often antibiotics (including metronidazole) are used for non‐antibacterial purposes in dogs and cats. This study looked to characterise the rationale for metronidazole prescription in these species. Methods Retrospective cohort study.
J. Ng   +11 more
wiley   +1 more source

Is sleep affected after microgravity and hypergravity exposure? A pilot study

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep is known to be affected in space travel and in residents of the international space station. But little is known about the direct effects of gravity changes on sleep, if other factors, such as sleep conditions, are kept constant. Here, as a first exploration, we investigated sleep before and after exposure to short bouts of microgravity ...
Barbara Le Roy   +9 more
wiley   +1 more source

Multiplex cytokine analysis of Werner syndrome.

open access: yesIntractable & Rare Diseases Research, 2015
We reported a minor inflammation-driven ageing (inflammageing) assessed by highly sensitive CRP (hsCRP) in normal individuals and patients with Werner syndrome (WS), followed by an ageing associated Th2-biased cytokine change in normal ageing in the ...
M. Goto   +5 more
semanticscholar   +1 more source

Herlyn-Werner-Wunderlich syndrome: A case report in a young woman, with literature review

open access: yesRadiology Case Reports, 2022
Herlyn-Werner-Wunderlich syndrome is a rare complex congenital disorder, with combined Müllerian and mesonephric duct anomalies, presenting with uterus didelphys, unilateral blind hemivagina and ipsilateral renal agenesis. Hemivaginal obstruction usually
Eduardo Negrão, MD   +4 more
doaj  

The future of paediatric sleep medicine: a blueprint for advancing the field

open access: yesJournal of Sleep Research, EarlyView.
Summary Paediatric sleep medicine has rapidly evolved and expanded over the past half century as it became increasingly recognised as a unique field related to but distinct from adult sleep medicine. In looking forward to the next years, the focus of the following discussion is two‐fold: to summarise a brief history of the field, recent developments ...
Angelika A. Schlarb   +9 more
wiley   +1 more source

Epigenetic Regulation of Werner Syndrome Gene in Age-Related Cataract

open access: yesJournal of Ophthalmology, 2015
Purpose. To examine the promoter methylation and histone modification of WRN (Werner syndrome gene), a DNA repair gene, and their relationship with the gene expression in age-related cataract (ARC) lens. Methods.
Xi Zhu, Guowei Zhang, L. Kang, H. Guan
semanticscholar   +1 more source

Assessing the relative influence of island climatic and geographical factors on body size in an endangered iguana species of the French Caribbean

open access: yesJournal of Zoology, EarlyView.
This study examines the influence of climatic and geographical factors on the body size of iguanas in the Lesser Antilles. We show that iguana body size increases with island size and decreases with distance from the mainland, suggesting that geographical conditions have a greater influence on body size compared to climatic conditions.
F. Desigaux   +6 more
wiley   +1 more source

Reprogramming Suppresses Premature Senescence Phenotypes of Werner Syndrome Cells and Maintains Chromosomal Stability over Long-Term Culture

open access: yesPLoS ONE, 2014
Werner syndrome (WS) is a premature aging disorder characterized by chromosomal instability and cancer predisposition. Mutations in WRN are responsible for the disease and cause telomere dysfunction, resulting in accelerated aging.
A. Shimamoto   +19 more
semanticscholar   +1 more source

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