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, 2019 The Werner syndrome is a segmental progeroid syndrome of adult onset characterized by the presence of multiple features resembling accelerated aging accompanied by rare tumors. Commonly, the first symptom is the lack of growth spurt during one’s teens.
Perona Abellón, Rosario +3 more
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Long-term follow-up of a case of bilateral elbow ulcers in a patient with Werner syndrome treated with pedicled radial forearm flaps [PDF]
Case Reports in Plastic Surgery & Hand SurgeryWerner syndrome is a rare autosomal recessive disorder caused by WRN gene mutations, leading to premature aging and genomic instability. Clinical symptoms include diabetes, skin lesions, and microvascular issues, with patients frequently developing ...
Yusuke Hayashibara +4 more
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Do you know this syndrome? Werner syndrome [PDF]
Anais Brasileiros de Dermatologia, 2017 : Werner syndrome is a rare autosomal recessive disorder, caused by mutations in the WRN gene. Clinical findings include: senile appearance, short stature, grey hair, alopecia, bird-like face, scleroderma-like skin changes, skin ulcers, voice ...
Özlem Bilgiç
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Herlyn-Werner-Wunderlich Syndrome: A Case Report
Journal of Nepal Medical Association, 2023 Herlyn-Werner-Wunderlich syndrome is a rare Mullerian and mesonephric ductal anomaly characterized by a triad of didelphys uterus, obstructed hemivagina, and ipsilateral renal agenesis complex.
Priyanka Vaidya +2 more
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Werner Syndrome Caused by Homozygous Frameshift Variant c.1578del in WRN [PDF]
Acta Medica LituanicaBackground. Progerias are rare hereditary genetic disorders that cause the onset of aging to occur earlier than generally expected, which initiates the progression of many age-related diseases.
Jovita Patricija Druta +3 more
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Herlyn–Werner–Wunderlich syndrome
Medical Journal of Dr. D.Y. Patil University, 2017 Herlyn–Werner–Wunderlich syndrome is a rare developmental anomaly, in which there is uterus didelphys with obstructed hemivagina and ipsilateral renal agenesis.
Himadri Bal +3 more
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Management of cataract in Werner syndrome
Indian Journal of Ophthalmology, 2018 Werner syndrome (WS) is a rare progressive disorder. It is characterized by the appearance of unusually accelerated aging (progeria) including bilateral senile cataract. Here, we report a successful management of hypermature cataract in WS.
Rakhi Kusumesh +3 more
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Herlyn Werner Wunderlich Syndrome with Hydrocolpos: A Case Report
Journal of Nepal Medical AssociationHerlyn-Werner-Wunderlich Syndrome is a very rare congenital malformation of the urogenital tract involving both the Mullerian and Wolffian ducts characterized by the triad uterine diadelphys, obstructed vagina, and unilateral renal agenesis.
Saurav Sen Oli +4 more
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WRN promotes bone development and growth by unwinding SHOX-G-quadruplexes via its helicase activity in Werner Syndrome [PDF]
Nature Communications, 2022 Short stature is a hallmark of Werner Syndrome, but the underlying mechanisms are not well studied. Here they report that WRN regulates bone development and growth by opening SHOX-G-quadruplexes via its helicase activity both in vitro and in vivo.
Yuyao Tian +9 more
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Herlyn Werner Wunderlich syndrome. Case report
Taiwanese Journal of Obstetrics & GynecologyObjective: Describe a clinical case of a patient with Herlyn Werner Wunderlich Syndrome in whom an accurate diagnosis was not made during menarche due to failures in her care and poor diagnostic suspicion.
Daniel Alberto Reyes-Martinez +5 more
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