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Surgery for West’s Syndrome

2002
Many cases of West's syndrome are inoperable, because there is no clear epileptic focus. In some cases, however, there is a structural abnormality which can be surgically removed. Dr. Hoffman discusses his experience with surgery for cortical dysplasia in West's syndrome.
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PERIVENTRICULAR LEUKOMALACIA AND WEST SYNDROME

Developmental Medicine & Child Neurology, 1996
SUMMARYThe authors studied the clinical course and electroencephalograms (ÉEGs) of 27 patients with periventricular leukomalacia (PVL), to investigate the relation betwéen PVL and West syndrome. Seven of the 27 patients with PVL developed WS; in all seven the PVL was severe. Bilateral parieto‐occipital dominant irregular polyspike‐and‐wave (PO‐polySpW)
A, Okumura   +3 more
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Epidemiology of West syndrome in Singapore

Brain and Development, 2001
The incidence of West syndrome (WS) was determined by a search of reports of electroencephalograms (EEG) recorded in 1998 and 1999 in all public hospitals in Singapore. Amongst records of patients born in 1998, nine were found with EEG features of hypsarrhythmia or modified hypsarrhythmia with onset of seizures between January 1,1998 and December 31 ...
W L, Lee, H T, Ong
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Pyretotherapy as Treatment in West's Syndrome

Clinical Electroencephalography, 1984
Four cases of West's syndrome (generalized myoclonic spasms, arrest of psychomotor development and hypsarrhythmia) which were found to be resistant to the classical treatment (ACTH, prednisone, nitrazepam, clonazepam, etc.) are reported. In these cases, high fever (pyretotherapy) induced by TBA vaccine (typhoid and paratyphoid) was used.
G O, Garcia de Alba   +2 more
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West syndrome with cerebellar porencephalus

Journal of Intellectual Disability Research, 1993
ABSTRACTThe authors report six very low birth weight newborn infants who had RDS, IVH and cerebellar porencephalus and later suffered from West syndrome. Four of them have been followed up to the present time and have had MRI scans performed. Their present clinico‐neurological features and MRI findings are described.
H, Koide, H, Shime
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Intracranial tumors and West syndrome

Pediatric Neurology, 1989
Two infants, 6 and 7 months of age, are reported with both West syndrome and cerebral tumors. In both patients, initial neurologic examinations were normal and tumor diagnoses were determined through routine imaging studies. Initial response to adrenocorticotrophic hormone treatment did not differ from that observed in patients with cryptogenic West ...
V, Ruggieri, R, Caraballo, N, Fejerman
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Induced microseizures in West syndrome

Brain and Development, 1991
Induced microseizures (IMS) were observed in a 5-month-old girl with symptomatic West syndrome. The seizures occurred following the suppression of infantile spasms with adrenocorticotropic hormone therapy and disappeared following the cessation of clonazepam administration.
K, Otani   +4 more
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Immunoglobulin therapy in the West syndrome

Brain and Development, 1987
An examination was made of high dose non-treated immunoglobulin (NTIG) therapy at an early stage of the West syndrome (WS). Six patients with cryptogenic WS who suffered attacks ranging from 15 days to 6 months (mean 70 days) and 5 patients with symptomatic WS who suffered attacks ranging from 14 days to 4 months (mean 32 days), were administered NTIG ...
M, Ariizumi   +6 more
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The West Syndrome: Developmental Aspects

Pediatrics International, 1987
AbstractThe electro‐clinical characteristics of childhood epilepsy are known to appear during the development of the brain and to change their features with age. Accordingly, developmental viewpoints are indispensable to researches on childhood epilepsy.Age‐dependent epileptic encephalopathy has the most remarkable developmental characteristics among ...
S, Ohtahara, Y, Ohtsuka, Y, Yamatogi
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West Syndrome Associated with Porencephaly

Pediatric Neurosurgery, 2008
A 3-year-old boy with West syndrome who was shown to have a cystic lesion on magnetic resonance imagings underwent surgical treatment. He had been initially managed with several antiepileptic drugs, but abnormalities on electroencephalography (EEG) persisted.
H, Katano   +6 more
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