Results 81 to 90 of about 3,088,136 (275)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
IgG and IgM western blot assay for diagnosis of congenital toxoplasmosis
Memorias do Instituto Oswaldo Cruz, 2010 The aim of this study was to evaluate the utility of western blot (WB) analysis as a diagnostic tool for congenital toxoplasmosis in 215 newborn infants.
Anderson S Machado +9 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Western Wind Quintet, November 2, 1979
, 2018 Recorded during a live performance at Oakland Recital Hall, Western Michigan University, Kalamazoo, Michigan, November 2, 1979, program no. 68 of the Department of Music's 1979-1980 season.Western Wind Quintet (Charles Osborne, flute ; Robert Humiston ...
Western Wind Quintet
core +2 more sources
Memorias do Instituto Oswaldo Cruz, 2007 The aim of this study was to test if serological distinction between patients with active and inactive neurocysticercosis (NCC), could be accomplished by the recognition of immunodominant peptides in total saline antigenic extract of Taenia solium ...
Ivanildes Solange da Costa Barcelos +4 more
doaj +1 more source
, 2019 Szakdolgozatomat a Testnevelési Egyetem Molekuláris Edzésélettani Kutató Központjában végeztem. Feladatom során a sirtuin enzim család, SIRT1 fehérjéjének mérésére Western blot illetve Kit technikát használtam.
Pajk, Melitta
core
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Western Brass Quintet, May 16, 1977
, 2018 Recorded during a live performance at Oakland Recital Hall, Western Michigan University, Kalamazoo, , May 16, 1977, program no. 240 of the Department of Music's 1976-1977 season.Western Brass Quintet (Donald Bullock, Stephen Jones, trumpets ; Neill ...
Western Brass Quintet
core +2 more sources
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source