Results 131 to 140 of about 641,848 (268)

The Reporter, April 1991 [PDF]

open access: yes, 2018
The Reporter is a publication produced by Western Carolina University featuring news, events, and campus community updates for faculty and staff. The publication began in August of 1970 and continues digitally today.
Western Carolina University;
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

The Reporter, June 1985 [PDF]

open access: yes, 2018
The Reporter is a publication produced by Western Carolina University featuring news, events, and campus community updates for faculty and staff. The publication began in August of 1970 and continues digitally today.
Western Carolina University;
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

AGENDA SETTING AND FRAMING DURING THE FIRST WAVE OF CORONAVIRUS PANDEMIC: A CONTENT ANALYSIS OF NEWS IN GREEK MEDIA

open access: yesAnthropological Researches and Studies
Objectives. Drawing heavily on theories focusing on the ways media represent health issues, and more specifically pandemics, the current research seeks to scrutinize the information conveyed by the Greek media to the public regarding the coronavirus ...
Michalis TASTSOGLOU   +3 more
doaj   +1 more source

Case Global: UN Commissioner for Human Rights Speaks at Case Western Reserve, draws world-wide media attention [PDF]

open access: yes, 2016
Vol. 8, #1 (2016) UN High Commissioner for Human Rights speaks at Case Western Reserve... (cover) Frederick K. Cox International Law Center celebrates 25 year anniversary Law school launches new Executive Master’s Degree in Financial Integrity Two ...
Case Western Reserve University School of Law
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

The Reporter, June 1988 [PDF]

open access: yes, 2017
The Reporter is a publication produced by Western Carolina University featuring news, events, and campus community updates for faculty and staff. The publication began in August of 1970 and continues digitally today.
Western Carolina University;
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Community-engaged flood mitigation and ecological restoration on a university campus

open access: yesEnvironmental Research: Ecology
Urban flooding is a major climate change risk that can be mitigated with green infrastructure such as tree plantings and restored naturalised buffers along watercourses.
Brendon Samuels   +2 more
doaj   +1 more source

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