Results 41 to 50 of about 641,848 (268)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Domestic Violence in the Canadian Workplace: Are Coworkers Aware?
Safety and Health at Work, 2016 Background: Domestic violence (DV) is associated with serious consequences for victims, children, and families, and even national economies. An emerging literature demonstrates that DV also has a negative impact on workers and workplaces.
Jennifer C.D. MacGregor +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
IEEE Access, 2018 As a dedicated countermeasure for heterogeneous multi-view data, multi-view clustering is currently a hot topic in machine learning. However, many existing methods either neglect the effective collaborations among views during clustering or do not ...
Pengjiang Qian +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Media metrics : how Arab and Western media construct success and failure in the ‘Global War on Terror’ [PDF]
, 2015 The media has played an important role in the ‘Global War on Terror’, and has received significant scholarly attention as a result. However, the way in which different media represent and construct notions of success and failure has been less well ...
Marsden, Sarah Victoria
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Riding the wave of fear, The rise of The Islamophobia Industry.
Ikhtilaf“Riding the wave of fear, The rise of The Islamophobia Industry.” Review of Nathan Lean. The Islamophobia Industry: How the Right Manufactures Fear of Muslims.
Oussama Boutehol, Larbi Touaf
doaj +1 more source
Contemporary media sport : de- or re-Westernization [PDF]
, 2008 Contemporary media sports culture is dominated by the West, and media sport studies has tended to focus on Western contexts. The Asia Pacific region is now a more significant feature of the global media sports cultural complex, however, through the ...
Gilmour, Callum, Rowe, David
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source