Results 51 to 60 of about 19,928,445 (236)

Multichannel Residual Conditional GAN-Leveraged Abdominal Pseudo-CT Generation via Dixon MR Images

open access: yesIEEE Access, 2019
Magnetic resonance (MR) images have distinctive advantages in radiation treatment (RT) planning due to their superior, anatomic and functional information compared with computed tomography (CT).
Ke Xu   +7 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Constructing a New 9/11: BBC Framing of Israeli Violence in Gaza after October 7

open access: yesİnsan & Toplum
The events of October 7, 2023, were reflexively framed in Western media discourse as a historical rupture comparable to September 11, 2001, reshaping public interpretations of the war in Gaza.
Hamdullah Baycar, Mehmet Rakipoğlu
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Location-Based Augmented Reality in Education

open access: yesEncyclopedia
Location-based Augmented Reality (AR) refers to educational mobile applications where a layer of digital content overlays the users’ physical environment when the users reach specific geographical locations.
Alexandros Kleftodimos   +1 more
doaj   +1 more source

Filtered in/filtered out: Locative media and social accessibility in urban spaces

open access: yesStudies in Communication Sciences, 2021
Social accessibility involves the capacity of a person to be reached by other people, typically through established social networks. Locative media provide new complications to the issue of social accessibility in urban spaces. They do not connect people
Darryl A. Pieber
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Integrating Augmented Reality and Geolocation for Outdoor Interactive Educational Experiences

open access: yesVirtual Worlds
This paper presents an augmented reality (AR) mobile application developed for Android devices, which brings five bust sculptures of historical personalities of the city of Komotini, Greece, to ‘life’ using the Unity engine.
Christos Mourelatos, Michalis Vrigkas
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Western String Chamber Orchestra, April 6, 1992

open access: yes, 2016
Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, April 6, 1992, 8:00 p.m., the 487th concert of the School of Music’s 1991-1992 season.Western String Chamber Orchestra, Bruce Uchimura ...
Western String Chamber Orchestra
core   +2 more sources

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