Results 61 to 70 of about 641,848 (268)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Integrating Augmented Reality and Geolocation for Outdoor Interactive Educational Experiences

open access: yesVirtual Worlds
This paper presents an augmented reality (AR) mobile application developed for Android devices, which brings five bust sculptures of historical personalities of the city of Komotini, Greece, to ‘life’ using the Unity engine.
Christos Mourelatos, Michalis Vrigkas
doaj   +1 more source

The Reporter, June 2009 [PDF]

open access: yes, 2017
The Reporter is a publication produced by Western Carolina University featuring news, events, and campus community updates for faculty and staff. The publication began in August of 1970 and continues digitally today.
Western Carolina University;
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Measuring Destination Image Using AI and Big Data: Kastoria’s Image on TripAdvisor

open access: yesSocieties
In recent years, the growing number of Online Travel Review (OTR) platforms and advances in social media and search engine technologies have led to a new way of accessing information for tourists, placing projected Tourist Destination Image (TDI) and ...
Anastasia Yannacopoulou   +1 more
doaj   +1 more source

Alienation and Precarious Contract Academic Staff in the Age of Neoliberalism

open access: yesConfero: Essays on Education, Philosophy and Politics, 2014
Not Available.
Kane Xavier Faucher
doaj   +1 more source

The Reporter, September 1998 [PDF]

open access: yes, 2018
The Reporter is a publication produced by Western Carolina University featuring news, events, and campus community updates for faculty and staff. The publication began in August of 1970 and continues digitally today.
Western Carolina University;
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Dynamic Anthropomorphism and Artificial Empathy in Conversational Agents: A Wizard-of-Oz Experimental Evaluation

open access: yesDigital
Conversational agents increasingly incorporate socio-emotional cues to support more natural and socially engaging digital interactions. Prior research has shown that anthropomorphism and artificial empathy influence user evaluations; however, these ...
Dimos Nanos, Georgios Lappas
doaj   +1 more source

The Reporter, September 1988 [PDF]

open access: yes, 2017
The Reporter is a publication produced by Western Carolina University featuring news, events, and campus community updates for faculty and staff. The publication began in August of 1970 and continues digitally today.
Western Carolina University;
core  

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