Results 51 to 60 of about 429,319 (212)

The effect of processing mode on the characteristics of crystalline sorbitol powder

open access: yesShipin yu jixie
ObjectiveThis study aimed to improve the fluidity of sorbitol to be used as a raw material for direct tablet pressing.MethodsXTAB290 crystalline sorbitol was sieved, and particles smaller than 50 mesh were further processed by fluidized bed granulation ...
YU Shankai   +5 more
doaj   +1 more source

Additive Manufacturing of High‐Performance Polymers for Extreme Environments

open access: yesAdvanced Science, EarlyView.
Additive manufacturing of high‐performance polymers for extreme environments is critically reviewed through an integrated chemistry‐processing‐structure‐property‐qualification framework. The review compares fused filament fabrication, selective laser sintering, and direct ink writing, linking rheology and thermal history to crystallization, defect ...
Md Tofazzal Hossain   +7 more
wiley   +1 more source

SeDeM-ODT diagrams of granules prepared under different levels of process variables (binder concentration and granulation time) by high shear wet granulation method.

open access: yes, 2021
SeDeM-ODT diagrams of granules prepared under different levels of process variables (binder concentration and granulation time) by high shear wet granulation method.
Amjad Khan (4021970)
core   +1 more source

Integrated O2 and H2 Gas Therapy via Microneedle‐Assisted Photocatalytic Water Splitting for Accelerating Diabetic Full‐Thickness Skin Wound Healing

open access: yesAdvanced Science, EarlyView.
A concept of integrated O2 and H2 gas therapy is achieved using a gas‐producing material. PMP nanoparticles, fabricated from platinum, MIL‐101(Fe)‐NH2, and phosphotungstic acid, are integrated into bilayer gelatin methacryloyl microneedles for transdermal delivery. These microneedles enable integrated O2 and H2 gas therapy and promote wound healing via
Zesheng Chen   +13 more
wiley   +1 more source

Simulation Modeling of a Pharmaceutical Tablet Manufacturing Process via Wet Granulation

open access: yesComplexity, 2019
The pharmaceutical tablet manufacturing process (PTMP) via wet granulation holds a critical position in pharmaceutical industry. The interest in integrating mechanistic process modeling into the pharmaceutical development has been increased because ...
Zhengsong Wang   +5 more
doaj   +1 more source

A Metal‐Polyphenol Self‐Assembled Coated 3D Sponge With Mild Photothermal Antibacterial, Exudate‐Controlling, and Immunomodulatory Functions for Hemostasis and Chronic Wound Healing

open access: yesAdvanced Science, EarlyView.
A thrombin‐functionalized copper‐polydopamine nanofiber sponge integrates rapid hemostasis, mild photothermal antibacterial therapy, stimulus‐responsive Cu2+ release, chemodynamic oxidative stress, and macrophage immunomodulation. This multifunctional dressing suppresses infection, regulates inflammation, promotes angiogenesis and re‐epithelialization,
Ziwei Zhang   +11 more
wiley   +1 more source

DEM modeling of high shear wet granulation of a simple system

open access: yesAsian Journal of Pharmaceutical Sciences, 2018
High shear wet granulation (HSWG) is one of the most poorly understood processes with known difficulties in optimization and scale up. The purpose of the current study is to develop a DEM model which can be applied under dynamic process conditions with ...
Saurabh Sarkar, Bodhisattwa Chaudhuri
doaj   +1 more source

A CD14‐Targeting In Situ Hydrogel Directs Macrophage Reprogramming to Minimize Scar Formation

open access: yesAdvanced Science, EarlyView.
A CD14‐targeting in situ hydrogel formed from a microbial polysaccharide rapidly remodels the immune microenvironment by reprogramming macrophage polarization, suppressing excessive inflammation, and coordinating tissue regeneration. This multifunctional hydrogel promotes scar‐reduced wound repair through enhanced angiogenesis, collagen remodeling, and
Rui Fang   +5 more
wiley   +1 more source

Improving solid dosage forms with dry granulation [PDF]

open access: yes, 2011
Although tablet manufacture is traditionally a batchbased wet granulation process, there are many advantages to be gained by adopting dry granulation, including lower costs and increased yields.
Smith, Geoff, Boswell, Steve
core   +5 more sources

Enhancing the Poor Flow and Tableting Problems of High Drug-Loading Formulation of Canagliflozin Using Continuous Green Granulation Process and Design-of-Experiment Approach

open access: yesPharmaceuticals, 2020
Maximization of drug-loading can significantly reduce the size of dosage form and consequently decrease the cost of manufacture. In this research, two challenges were addressed: poor flow and tableting problems of high-drug loading (>70%) formulation of ...
Bjad K. Almutairy   +8 more
doaj   +1 more source

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