High-Speed Tableting of High Drug-Loaded Tablets Prepared from Fluid-Bed Granulated Isoniazid
Pharmaceutics, 2023 The aim of this feasibility study was to investigate the possibility of producing industrial-scale relevant, robust, high drug-loaded (90.9%, w/w) 100 mg dose immediate-release tablets of isoniazid and simultaneously meet the biowaiver requirements. With
Valentyn Mohylyuk, Dace Bandere
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Real-time assessment of critical quality attributes of a continuous granulation process [PDF]
, 2013 There exists the intention to shift pharmaceutical manufacturing of solid dosage forms from traditional batch production towards continuous production. The currently applied conventional quality control systems, based on sampling and time-consuming off ...
Córdoba Díaz, Damián +6 more
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Influence of process variables on the properties of simvastatin self-emulsifying granules obtained through high shear wet granulation [PDF]
, 2015 Improvements of the oral bioavailability of lipophilic drugs can be obtained using lipidic formulations such as the self-emulsifying drug delivery systems.
Benda L. +5 more
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Wet granulation in laboratory-scale high shear mixers: Effect of chopper presence, design and impeller speed [PDF]
, 2011 The effect of the main means of agitation in a high shear mixer has been investigated in this study. Granulation runs have been performed on a fine cohesive microcrystalline cellulose powder (Avicel 105, d50 = 20 μm) often used as a pharmaceutical ...
Chitu, Toma Mihai +2 more
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Discrete element modelling of fluidised bed spray granulation [PDF]
, 2002 A novel discrete element spray granulation model capturing the key features of fluidised bed hydrodynamics, liquid-solid contacting and agglomeration is presented.
Boerefijn, R. +3 more
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PREPARATION AND EVALUATION OF SUSTAINED-RELEASE DICLOFENAC SODIUM TABLETS
Zagazig Journal of Pharmaceutical Sciences, 2008 The aim of this work is to prepare and evaluate sustained-release matrix diclofenac sodium (DS) tablets using simple diluents by either direct compression or wet granulation techniques. The prepared tablets were evaluated for physical characteristics and
Hussein Sayed +2 more
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Formulation, Characterization and Physicochemical Evaluation of Potassium Citrate Effervescent Tablets [PDF]
Advanced Pharmaceutical Bulletin, 2013 Purpose: The aim of this study was to design and formulation of potassium citrate effervescent tablet for reduction of calcium oxalate and urate kidney stones in patients suffering from kidney stones. Methods: In this study, 13 formulations were prepared
Fatemeh Fattahi, Abolfazl Aslani
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Comprehensive review on modern techniques of granulation in pharmaceutical solid dosage forms
Intelligent PharmacyThis comprehensive review explores modern granulation techniques in pharmaceutical dosage forms along with conventional methods, focusing on dry granulation and wet granulation.
Anil Kumar Vadaga +4 more
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Formulation and evaluation of theophylline sustained release matrix tablets using synthetic polymers
Journal of Applied Pharmaceutical Research, 2022 The aim of present work was to develop theophylline sustained release tablets which could improve patient compliance towards the effective management of asthma The polymers, HPMC (Hydroxy propyl methyl cellulose) K4M, HPMC K100M, Eudragit, Chitosan in ...
Navdeep Kaur, Mohit Kumar
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Wet granulation multiscale modelling accelerated via CG-DEM [PDF]
EPJ Web of ConferencesWet agglomeration is a complex particulate process driven by multiple microscale mechanisms. Discrete Element Modeling (DEM) enables a deeper understanding of these mechanisms and supports process optimization.
Saghafian Larijani Roxana +2 more
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