Effect of operating conditions and physico–chemical properties on the wet granulation kinetics in high shear mixer [PDF]
, 2009 The wet granulation process is sensitive to changes in product properties and process variables. The optimal process and formulation are based on the knowledge of the granule growth mechanisms and of the effects of product properties and process ...
Hemati, Mehrdji +2 more
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STEAM GRANULATION VERSUS WET GRANULATION: IMPACT ON GRANULE AND TABLETS PROPERTIES
, 2023 Steam granulation (SG) involves the use of steam as the granulating medium instead of traditional liquid water [1]. Steam provides a higher diffusion rate into the powder bed and a more favourable thermal balance during the drying step.
Giulia De Santi +5 more
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Quantitative Assessment of Mass Flow Boundaries in Continuous Twin-screw Granulation
CHIMIA, 2016 In pharmaceutical manufacturing, there is an increasing interest in continuous manufacturing. As an example for fast continuous processes in general of considerable complexity, this study was focussed on improving the understanding of twin-screw
Adrian Schmidt +4 more
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Melt granulation as an alternative technique in solid dosage forms manufacture [PDF]
Arhiv za farmaciju, 2015 Conventional granulation methods are associated with significant disadvantages which have led to increased interest and investment in the development of alternative techniques.
Aleksić Ivana +4 more
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Wet granulation to overcome liquisolid technique issues of poor flowability and compactibility: A study to enhance Glibenclamide dissolution [PDF]
The aim of this study is to apply wet granulation on liquisolid powders to overcome issues of poor powder flowability and compressibility especially with using high viscosity liquid vehicles.
Javaheri, H. +2 more
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EVALUATION AND BIOAVAILABILITY OF PHENAZOPYRIDINE HYDROCHLORIDE TABLETS PREPARED WITH COMPACTROL [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 1985 Phenazopyridine hydrochloride tablets were prepared at different packing fractions using the newly introduced direct compressible vehicle "compactrol". Tablets were also prepared with avicel and wet granulation technique for comparison.
Abdel-Gawad Abdel-Gawad +2 more
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Разработка и регистрация лекарственных средств, 2021 Introduction. The stage of wet granulation is often used in the technology of solids. The method of wet granulation in a mixer-granulator with high shear force can be regarded as the most complicated method of its implementation from the engineering and ...
O. N. Abrosimova, M. A. Burakova
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Formulation of atenolol granules prepared by high shear wet granulation.
, 2021 Formulation of atenolol granules prepared by high shear wet granulation.
Amjad Khan (4021970)
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Virtual prototyping of wet granulation processes [PDF]
, 2023 Wet granulation processes are essential in various industries, such as pharmaceuticals, where they play a critical role in enhancing the flowability, compressibility, and homogeneity of powder blends -- properties essential for high-quality manufacturing.
Plath, Timo; id_orcid +5 more
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High-Speed Tableting of High Drug-Loaded Tablets Prepared from Fluid-Bed Granulated Isoniazid
Pharmaceutics, 2023 The aim of this feasibility study was to investigate the possibility of producing industrial-scale relevant, robust, high drug-loaded (90.9%, w/w) 100 mg dose immediate-release tablets of isoniazid and simultaneously meet the biowaiver requirements. With
Valentyn Mohylyuk, Dace Bandere
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