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Advances in Twin-Screw Granulation

open access: yesPharmaceutics, 2021
Twin-screw granulation (TSG) is an emerging process technology that allows both wet and dry granulation of powders with a wide range of properties [...]
Valérie Vanhoorne, Ashish Kumar
doaj   +2 more sources

Parametric Study of Residence Time Distributions and Granulation Kinetics as a Basis for Process Modeling of Twin-Screw Wet Granulation [PDF]

open access: yesPharmaceutics, 2021
Twin-screw wet granulation is a crucial unit operation in shifting from pharmaceutical batch to continuous processes, but granulation kinetics as well as residence times are yet poorly understood.
Timo Plath   +3 more
doaj   +2 more sources

Improved wet granulation techniques [PDF]

open access: yesFarmacja Polska, 2020
Wet granulation is one of the most frequently used processes in the pharmaceutical industry to manufacture solid dosage forms. Wet granulation is helpful in tableting active substances that are not susceptible to the compression.
Monika Pastewska, Wiesław Sawicki
doaj   +1 more source

In situ wet pharmaceutical granulation captured using synchrotron radiation based dynamic micro-CT

open access: yesJournal of Synchrotron Radiation, 2023
Synchrotron radiation based dynamic micro-computed tomography (micro-CT) is a powerful technique available at synchrotron light sources for investigating evolving microstructures. Wet granulation is the most widely used method of producing pharmaceutical
Xiao Fan Ding   +3 more
doaj   +1 more source

Continuous Twin Screw Granulation: A Review of Recent Progress and Opportunities in Formulation and Equipment Design

open access: yesPharmaceutics, 2021
Continuous twin screw wet granulation is one of the key continuous manufacturing technologies that have gained significant interest in the pharmaceutical industry as well as in academia over the last ten years.
Christoph Portier   +2 more
doaj   +1 more source

Physical, Mechanical, and Environmental Properties of Corn Stalk Fiber Reinforced Braking Composites Prepared by Wet Granulation

open access: yesJournal of Natural Fibers, 2022
Due to the increasing concern with the environmental safety and recyclability, natural fiber-reinforced composites have attracted more and more attention. In the present work, braking composite samples with and without wet granulation were fabricated and
Yucheng Liu   +7 more
doaj   +1 more source

Granulation techniques and technologies: recent progresses [PDF]

open access: yesBioImpacts, 2015
Granulation, the process of particle enlargement by agglomeration technique, is one of the most significant unit operations in the production of pharmaceutical dosage forms, mostly tablets and capsules.
Srinivasan Shanmugam
doaj   +1 more source

Wet granulation in laboratory scale high shear mixers: Effect of binder properties [PDF]

open access: yes, 2011
The effect of binder properties on torque curves, granule growth kinetics, wet mass consistency and dry granule strength has been investigated in this study.
Hemati, Mehrdji   +5 more
core   +1 more source

Wet granulation in laboratory-scale high shear mixers: Effect of chopper presence, design and impeller speed [PDF]

open access: yes, 2011
The effect of the main means of agitation in a high shear mixer has been investigated in this study. Granulation runs have been performed on a fine cohesive microcrystalline cellulose powder (Avicel 105, d50 = 20 μm) often used as a pharmaceutical ...
Hemati, Mehrdji   +5 more
core   +1 more source

A STUDY ON THE STABILITY OF DIRECTLY COMPRESSED OXYTETRACYCLINE HYDROCHLORIDE AND DIIODOQUIN TABLETS [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 1984
A study on the stability of directly compressed oxytetracycline hydrochloride and diiodoquin tablets was preformed. A comparison was made between diiodoquin tablets prepared by direct compression and those prepared by wet granulation.
S. Tout, A. Aboutaleb
doaj   +1 more source

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