Results 261 to 270 of about 57,794 (383)

Identification of Angiogenesis-Related Gene Signatures and Prediction of Potential Therapeutic Targets in Ulcerative Colitis Using Integrated Bioinformatics

Journal of Inflammation Research
Xijuan Xu,1,* Hongan Ying,2,* Xiaozhi Wang,1 Weiwen Hong,1 Meng Zhang3 1Department of Anus & Intestine Surgery, Taizhou First People’s Hospital, Taizhou, Zhejiang, People’s Republic of China; 2Department of Geriatrics, Taizhou First People’s ...
Xu X, Ying H, Wang X, Hong W, Zhang M
doaj  

Artificial intelligence driven multi-omics framework identifies COL6A3 as a diagnostic biomarker and a putative gene target modulated by Embelin in Colorectal cancer. [PDF]

Front Oncol
Javali PS, Thirumurugan K.
europepmc   +1 more source

Chromosome‐Level Genome and Organ‐Specific Transcriptome of Alnus glutinosa Uncover Lineage‐Specific Innovations in Root Nodule Symbiosis

Plant, Cell &Environment, EarlyView.
ABSTRACT Alnus glutinosa is one of only three lineages within the order Fagales capable of establishing root nodule symbiosis (RNS). Although a fragmented genome assembly of A. glutinosa was previously available, its limited quality, combined with the lack of comprehensive transcriptomic resources, has constrained in‐depth comparative and functional ...
Zijian Liu, Xiaoxiao Zhao, Xiuli li, Yong Feng, Linnan Wu, Zhen Wu, Yao Zhong, Qingcheng Qiu, Bo Song, Hang Zhao, Hongbing Liu, Shifeng Cheng   +11 more
wiley   +1 more source

Immune involvement in neuropsychiatric disorders: Insights from single‐cell transcriptomic studies

Psychiatry and Clinical Neurosciences, EarlyView.
Neuropsychiatric disorders pose profound challenges to both research and treatment, largely due to their clinical heterogeneity and the limited understanding of their underlying biological mechanisms. While bulk RNA sequencing (bulk RNA‐seq) has been widely used to study gene expression, it cannot resolve cell‐type‐specific signals or detect rare ...
Tsutomu Takeda, Michihiro Toritsuka, Hiroto Tamakoshi, Nakao Iwata, Manabu Makinodan   +4 more
wiley   +1 more source

Transcriptome and weighted gene co-expression network analysis identify hub genes and pathways in rat kidneys after deep hypothermic circulatory arrest. [PDF]

Ren Fail
Wang L, Lin Z, Lin Y, Wu Q, Zhong G, Chen L.   +5 more
europepmc   +1 more source

Elevational variation in heart mass and suppression of hypoxia‐induced right ventricle hypertrophy in Andean leaf‐eared mice (Phyllotis)

The Journal of Physiology, EarlyView.
Abstract figure legend In lowland mammals that ascend to high elevation, hypoxia‐induced changes in the pulmonary circulation can give rise to hypoxic pulmonary hypertension (HPH) and associated right‐ventricle (RV) hypertrophy. Andean mice with broad elevational ranges have greater heart mass relative to body size at higher elevations, but they ...
Naim M. Bautista, Nathanael D. Herrera, Marcial Quiroga‐Carmona, Chandrasekhar Natarajan, Adriana Rico‐Cernohorska, Jorge Salazar Bravo, Graham R. Scott, Guillermo D'Elía, Zachary A. Cheviron, Jay F. Storz   +9 more
wiley   +1 more source

Hyperlipidemia-associated specific modules and hub genes revealed by integrative methods of WGCNA and MetaDE. [PDF]

Front Genet
Zhao Z, Cao Y, Gu A, Yao H.
europepmc   +1 more source

Identification of key pathways and genes in different types of chronic kidney disease based on WGCNA

, 2019
Yuhe Guo, Junjie Ma, Lanyan Xiao, Jiali Fang, Guanghui Li, Lei Zhang, Lu Xu, Xingqiang Lai, Guanghui Pan, Zheng Chen   +9 more
openalex   +2 more sources

Additional file 5 of GAS6-AS1, a long noncoding RNA, functions as a key candidate gene in atrial fibrillation related stroke determined by ceRNA network analysis and WGCNA

, 2023
Rui-bin Li, Xiaohong Yang, Jidong Zhang, Wei Cui   +3 more
openalex   +1 more source

Identification of Crucial Drug Targets and Pathways to Reprogram Drug Resistance Through Epigenetic Modulation in Advanced Lung Cancer Using Integrated Bioinformatics Approach

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman, Mossammat Rima Akter, Nur Alam   +2 more
wiley   +1 more source