The effect of cold ischemia time on hypoxia, EMT, and apoptosis pathways in normal colon mucosa. [PDF]
Duzowska K +12 more
europepmc +1 more source
Peer Review #1 of "Identification of crucial genes in abdominal aortic aneurysm by WGCNA (v0.1)"
Siliang Chen +99 more
openalex +2 more sources
Embryonic Hormetic Priming Modulates Later‐Life Thermal Tolerance
This study investigates how early‐life thermal environments affect later thermal tolerance in the black‐lip pearl oyster, Pinctada margaritifera. Developmental thermal priming had contrasting, family‐specific effects on thermal tolerance, with conserved stress‐response pathways but evidence of priming‐induced regulatory network reorganization.
K. Lugue +7 more
wiley +1 more source
Transcriptomic analysis and machine learning have identified shared diagnostic genes and a possible mechanism linking bipolar disorder and epilepsy. [PDF]
Zhang Y, Xu Y, Huo C.
europepmc +1 more source
We performed combined proteome and transcriptome analysis of human isotype‐defined B cell subsets. IgG4‐switched B cells were most distinct from naive B cells in terms of mRNA as well as protein expression profiles. SDR16C5 was identified as uniquely upregulated in IgG4‐switched B cells.
Jana Koers +6 more
wiley +1 more source
Identification of core genes mediating the association between obesity and hepatocellular carcinoma: A bioinformatics study based on mitochondrial metabolism and immune pathways. [PDF]
Li X, Min R.
europepmc +1 more source
WGCNA-pipeline-for-Alfalfa: v2.0.0: Advanced Analysis Pipeline & 16GB RAM Optimization
Li, Jiaqing, Lei, Huanwei
openalex +1 more source
Identification of Prognostic Biomarkers KLK13 and SLC5A8 in Canine Melanoma via Transcriptomics and WGCNA Analysis [PDF]
Heyi Zhao, Zixiang Lin, Hua Yao
openalex +1 more source
Human Systems Immunology in the Omics Era: Challenges, Methods, and Emerging Directions
Systems immunology provides a transformative framework for decoding human immune complexity. This review evaluates high‐throughput technologies and provides a roadmap for navigating analytical challenges—such as batch effects and interindividual heterogeneity—to successfully translate multimodal data into meaningful biological insights.
Lennart Riemann, Reinhold Förster
wiley +1 more source

