Results 91 to 100 of about 1,520,238 (297)

A Conjugation Delivery System of Macrophages and Platelet Pharmacytes Promotes Regeneration After Spinal Cord Injury

Advanced Science, EarlyView.
A macrophage–platelet conjugation system (M‐P‐NPs@PPARγ) targets injure tissue to co‐deliver platelet mitochondria and PPARγ‐encoding NPs. This strategy boosts the macrophage energy supply and restores lipid homeostasis, leading to synergistically enhanced efferocytosis and tissue repair Abstract Mitochondrial dysfunction occurs in macrophages with ...
Haoli Wang, Hao Hu, Yijun Li, Lintao Hu, Chenhui Gu, Yiwei Zhu, Jing Huang, Na Li, Shuqi Jiang, Shouyan Zu, Jiachen Xu, Yining Wang, Ke Yang, Pengfei Chen, Liqing Shangguan, Yongcheng Wang, Shunwu Fan, Xianfeng Lin, Qingqing Wang   +18 more
wiley   +1 more source

Autopolyploidization‐Induced Chromatin Remodeling Regulates Leaf Size Variation in Brassica rapa

Advanced Science, EarlyView.
This study demonstrates that monoploid, diploid, and autotetraploid Brassica rapa lines derived from the same genome exhibit distinct leaf morphology. Ploidy changes remodel chromatin accessibility and histone modifications to regulate gene expression, while key transcription factors BrGRF13 and BrARF11 control leaf size and polarity, driving ...
Haoyuan Dong, Yanhong Liu, Yuanming Liu, Shuxin Xuan, Huanhuan Chen, Lai Wei, Guibao Zhang, Hongcui Pei, Zilong Dai, Yanhua Wang, Jinzhu Qiao, Shuangxia Luo, Xueping Chen, Yiguo Hong, Jianjun Zhao, Shuxing Shen, Zefu Lu, Aixia Gu   +17 more
wiley   +1 more source

Transcriptome dynamics and allele-specific regulation underlie wheat heterosis at the anthesis and grain-filling stages

BMC Genomics
Background As wheat is a globally important staple crop, the molecular regulatory network underlying heterosis in wheat remains incompletely understood. The flag leaf is the primary source of photoassimilates during grain filling and plays a crucial role
Xiaojun Wu, Xiangdong Chen, Ren Wang, Haoquan Wang, Xigui Hu, Yuquan Wang, Gan Li, Na Dong, Tiezhu Hu, Zhengang Ru   +9 more
doaj   +1 more source

Wheat Bran Phenolic Acids: Bioavailability and Stability in Whole Wheat-Based Foods [PDF]

, 2015
Barbara Laddomada, Sofia Caretto, Giovanni Mita   +2 more
openalex   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

The bHLH transcription factor PIL1 orchestrates starch synthesis in key cereal crops

Nature Communications
Key cereal crops, including wheat, rice and maize, supply nearly 50% of the world’s caloric intake, with starch constituting over 70% of the grain weight. However, the regulatory mechanisms underlying starch synthesis are poorly understood. In this study,
Yanjun Meng, Jiaxing Cui, Wenbo Zeng, Xiaopei Li, Changqing Du, Pengfei Wang, Gezi Li, Qiang Ge, Tiancai Guo, Guozhang Kang   +9 more
doaj   +1 more source

Irrigation Differentially Impacts Populations of Indigenous Antibiotic-Producing Pseudomonas spp. in the Rhizosphere of Wheat [PDF]

, 2012
Olga V. Mavrodi, Dmitri V. Mavrodi, James A. Parejko, Linda S. Thomashow, David M. Weller   +4 more
openalex   +1 more source

Genetic Variability for Grain Components Related to Nutritional Quality in Spelt and Common Wheat [PDF]

, 2023
Ana Belén Huertas-García, Facundo Tabbita, Juan B. Álvarez, Josefina C. Sillero, María Itria Ibba, Marianna Rakszegi, Carlos Guzmán   +6 more
openalex   +1 more source

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source

Comparative transcriptome analysis reveals the impact of daily temperature difference on male sterility in photo-thermo-sensitive male sterile wheat

BMC Genomics
Background Photo-thermo-sensitive male sterility (PTMS), which refers to the male sterility triggered by variations in photoperiod and temperature, is a crucial element in the wheat two-line hybrid system. The development of safe production and efficient
Fuqiang Niu, Zihan Liu, Yongjie Liu, Jianfang Bai, Tianbao Zhang, Shaohua Yuan, Xiucheng Bai, Changping Zhao, Fengting Zhang, Hui Sun, Liping Zhang, Xiyue Song   +11 more
doaj   +1 more source