Whipworm and roundworm infections [PDF]
Nature Reviews Disease Primers, 2020 Trichuriasis and ascariasis are neglected tropical diseases caused by the gastrointestinal dwelling nematodes Trichuris trichiura (a whipworm) and Ascaris lumbricoides (a roundworm), respectively.
Kathryn J Else +2 more
exaly +13 more sources
Trichuris muris whey acidic protein induces type 2 protective immunity against whipworm. [PDF]
PLoS Pathogens, 2018 Human whipworm (Trichuris trichiura) infects approximately 1 in 15 people worldwide, representing the leading infectious cause of colitis and subsequent, inflammatory bowel disease (IBD).
Neima Briggs +14 more
doaj +5 more sources
Bacterial contact induces polar plug disintegration to mediate whipworm egg hatching.
PLoS Pathogens, 2023 The bacterial microbiota promotes the life cycle of the intestine-dwelling whipworm Trichuris by mediating hatching of parasite eggs ingested by the mammalian host.
Amicha Robertson +15 more
doaj +4 more sources
Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo. [PDF]
PLoS Neglected Tropical Diseases, 2017 Trichuris trichiura is a human parasitic whipworm infecting around 500 million people globally, damaging the physical growth and educational performance of those infected.
Frederick A Partridge +11 more
doaj +3 more sources
EFSA Journal, 2019 Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on viable embryonated eggs of the whipworm Trichuris suis as a novel food (NF) pursuant to Regulation (EU)
Alexandre Maciuk +2 more
exaly +3 more sources
Widespread Trichuris incognita reveals hidden diversity and reshapes understanding of human whipworm infections [PDF]
Nature CommunicationsSoil-transmitted helminthiases, particularly trichuriasis, affect over 500 million people, mostly in low- and middle-income countries. Traditional diagnostics fail to distinguish between Trichuris species, obscuring transmission patterns and treatment ...
Nurudeen Rahman +9 more
doaj +3 more sources
An Unpleasant Souvenir: Whipworm as an Incidental Finding During a Screening Colonoscopy [PDF]
Journal of Investigative Medicine High Impact Case ReportsTrichuriasis is a neglected tropical disease caused by Trichuris trichiura that spreads through the ingestion of embryonated eggs in contaminated soil, water, or food.
Lefika Bathobakae MD, MPH +8 more
doaj +3 more sources
Bacteria-induced egg hatching differs for Trichuris muris and Trichuris suis [PDF]
Parasites & Vectors, 2015 Background Eggs of the porcine whipworm Trichuris suis are currently explored in human clinical trials as a treatment of immune-mediated diseases. In this context, only the infective, embryonated eggs, constitute the Active Pharmaceutical Ingredient (API)
Nermina Vejzagić +5 more
doaj +2 more sources
A drug repurposing screen for whipworms informed by comparative genomics. [PDF]
PLoS Neglected Tropical Diseases, 2023 Hundreds of millions of people worldwide are infected with the whipworm Trichuris trichiura. Novel treatments are urgently needed as current drugs, such as albendazole, have relatively low efficacy.
Avril Coghlan +14 more
doaj +2 more sources
Genome and transcriptome of the porcine whipworm Trichuris suis [PDF]
Nature Genetics, 2014 Trichuris (whipworm) infects 1 billion people worldwide and causes a disease (trichuriasis) that results in major socioeconomic losses in both humans and pigs.
Aaron R Jex +2 more
exaly +4 more sources