Results 21 to 30 of about 3,973 (202)

Sedimentary ancient DNA as part of a multimethod paleoparasitology approach reveals temporal trends in human parasitic burden in the Roman period. [PDF]

PLoS Neglected Tropical Diseases
The detection of parasite infections in past populations has classically relied on microscopic analysis of sediment samples and coprolites. In recent years, additional methods have been integrated into paleoparasitology such as enzyme-linked ...
Marissa L Ledger, Tyler J Murchie, Zachery Dickson, Melanie Kuch, Scott D Haddow, Christopher J Knüsel, Gil J Stein, Mike Parker Pearson, Rachel Ballantyne, Mark Knight, Koen Deforce, Maureen Carroll, Candace Rice, Tyler Franconi, Nataša Šarkić, Saša Redžič, Erica Rowan, Nicholas Cahill, Jeroen Poblome, Maria de Fátima Palma, Helmut Brückner, Piers D Mitchell, Hendrik Poinar   +22 more
doaj   +2 more sources

Chronic whipworm infection exacerbates Schistosoma mansoni egg-induced hepatopathology in non-human primates

Parasites & Vectors, 2020
Background Schistosomiasis continues to inflict significant morbidity and mortality in the tropical and subtropical regions of the world. The disease endemicity overlaps with the transmission of other parasitic diseases.
Loc Le, Sabiha Khatoon, Paola Jiménez, Christopher Peterson, Rebecca Kernen, Weidong Zhang, Adebayo J. Molehin, Samra Lazarus, Justin Sudduth, Jordan May, Souvik Karmakar, Juan U. Rojo, Gul Ahmad, Workineh Torben, David Carey, Roman F. Wolf, James F. Papin, Afzal A. Siddiqui   +17 more
doaj   +2 more sources

The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function

Nature Communications, 2019
In the study, the authors identify a protein excreted by the parasite Trichuris muris, p43, which can modulate IL-13 function, a key cytokine involved in host protection.
Allison J. Bancroft, Colin W. Levy, Thomas A. Jowitt, Kelly S. Hayes, Seona Thompson, Edward A. Mckenzie, Matthew D. Ball, Eamon Dubaissi, Aidan P. France, Bruno Bellina, Catherine Sharpe, Aleksandr Mironov, Sheila L. Brown, Peter C. Cook, Andrew S. MacDonald, David J. Thornton, Richard K. Grencis   +16 more
doaj   +2 more sources

Magnified Endoscopic Observations of a Living Whipworm

Internal Medicine, 2020
An asymptomatic 64-year-old man with a colonic polyp was referred to our department. He underwent colonoscopy and a whitish worm was detected in the transverse colon (Picture 1a). Narrow band imaging revealed a whole parasite body (Picture 1b).
K. Hotta, K. Imai, S. Ito
semanticscholar   +4 more sources

Whipworm Found During a Colonoscopy

ACG Case Reports Journal, 2019
A 78-year-old man underwent a surveillance colonoscopy after a previous large polypectomy. He was otherwise healthy and had no concerning symptoms. He had recently traveled to South Africa and Thailand. He had a remote history of traveling to East Africa
Xiao Jing Wang, J. Eaton
semanticscholar   +3 more sources

A new species of whipworm from a south american hystricomorph rodent

Memorias Do Instituto Oswaldo Cruz, 1990
A new species of whipworm, Trichuris robusti, is described from the cecum and large intestine of rodent, Ctnomys robusti, collected in northern Chile. The nematode shows close affinityto T. bradleyi and T. chilensis, both having been described from Chile
B. B. Babero, R. B. Murua
exaly   +3 more sources

Bacillus thuringiensis Cry14A family proteins as novel anthelmintics against gastrointestinal nematode parasites. [PDF]

PLoS Neglected Tropical Diseases
Bacillus thuringiensis crystal (Cry) proteins have been expressed in commercial transgenic crops for nearly 30 years, providing safe and effective control of insect pests and significantly reducing the application of hazardous chemical pesticides.
Duy Hoang, Kelly Flanagan, Qian Ding, Nicholas R Cazeault, Hanchen Li, Stefani Díaz-Valerio, Florentina Rus, Esther A Darfour, Elizabeth Kass, Katherine H Petersson, Martin K Nielsen, Heiko Liesegang, Gary R Ostroff, Raffi V Aroian   +13 more
doaj   +2 more sources

Vaccination Against Whipworm: Identification of Potential Immunogenic Proteins in Trichuris muris Excretory/Secretory Material

Scientific Reports, 2018
Trichuris trichiura (whipworm) is one of the four major soil-transmitted helminth infections of man, affecting an estimated 465 million people worldwide. An effective vaccine that induces long-lasting protective immunity against T.
David J. Thornton, Thornton, David; id_orcid, Rebecca K. Shears, Grencis, Richard, Bancroft, Allison, Allison J. Bancroft, Shears, Rebecca, Catherine Sharpe, Sharpe, Catherine, Richard K. Grencis   +9 more
core   +2 more sources

The whipworm (Trichuris suis) secretes prostaglandin E2 to suppress proinflammatory properties in human dendritic cells

The FASEB Journal, 2017
Clinical trials have shown that administration of the nematode Trichuris suis can be beneficial in treating various immune disorders. To provide insight into themechanisms by which this wormsuppresses inflammatory responses, an active component was ...
Williams, Andrew R., Cummings, R.D., Stavenhagen, Kathrin, Kalay, H., Laan, Lisa C, Nejsum, P., Dijkstra, Christine D., Laan, L.C., Vlasakov, I., Williams, A.R., Giera, M., Dijkstra, C.D., , I. van die, Williams, Andrew R, Dijkstra, Christine D, Wuhrer, M., Giera, Martin, Vlasakov, Iliyan, Nejsum, Peter, Kooij, G., Stavenhagen, K., Kalay, Hakan, Cummings, Richard D., Thamsborg, Stig M., Kooij, Gijs, Thamsborg, S.M., Thamsborg, Stig M, Van Die, Irma, Kringel, H., Laan, Lisa C., Kringel, Helene, Cummings, Richard D, Wuhrer, Manfred   +32 more
core   +2 more sources

The immunomodulatory p43 secreted protein of Trichuris whipworm parasites is a lipid carrier that binds signalling lipids and precursors. [PDF]

Sci Rep
Parasitic helminths such as the Trichuris whipworms contribute to significant disease and morbidity in humans and other animals. They cause prolonged infections despite intact immune systems of their hosts, and their persistence is increasingly ...
Kennedy MW, Bancroft AJ, Grencis RK.
europepmc   +2 more sources