Results 51 to 60 of about 160,130 (306)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Flow-sensing mechanisms and biomimetic potential of seal whiskers [PDF]

open access: yes, 2022
Seals can accurately track fish trails as far as 180 m away solely using ultrasensitive whiskers. A high-aspect-ratio bluff body vibrates due to its shedding vortices when the oncoming flow is present, or it is being towed in still water.
Zheng, Xingwen, Zheng, Xingwen; id_orcid
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Luminescent analysis of the quality of CdS nanocrystals depending on technological parameters

open access: yesSemiconductor Physics, Quantum Electronics & Optoelectronics, 2019
This work is devoted to luminescent investigations of CdS nanowhiskers grown in different technological approaches with variable parameters, what allows to control sizes and morphology of grown nanocrystals. Luminescence was used for the express analysis
A.B. Bogoslovskaya
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

In Vivo Visualization of Active Polysynaptic Circuits With Longitudinal Manganese-Enhanced MRI (MEMRI)

open access: yesFrontiers in Neural Circuits, 2018
Manganese-enhanced magnetic resonance imaging (MEMRI) is a powerful tool for in vivo non-invasive whole-brain mapping of neuronal activity. Mn2+ enters active neurons via voltage-gated calcium channels and increases local contrast in T1-weighted images ...
Suellen Almeida-Corrêa   +2 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Tensile testing of SiC whiskers [PDF]

open access: yes, 1984
The room temperature tensile mechanical properties of SiC whiskers have been examined using a micro-tensile-test apparatus. SiC whiskers exhibit an average tensile strength of 8.4 GPa for a 5 mm tested length, and an average elastic modulus of 581 GPa ...
Petrovic, J. J.
core  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Wonders of Harbor and Grey Seal Whiskers: Morphology, Natural Frequencies, and 3D Modeling

open access: yesAdvanced Science
Seals can track fish using highly sensitive whiskers; however, the extent to which their morphologically diverse whiskers respond to hydrodynamic signals across frequencies remains unexplored.
Xingwen Zheng   +4 more
doaj   +1 more source

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