Results 151 to 160 of about 2,829,195 (234)

Triggered Calcium Lightning Programs Cochlear Development

Exploration, EarlyView.
Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma, Hai‐Peng Wang, Yu‐Meng Jiang, Ke Lai, Ming‐Xian Li, Zhen Zhang, Li‐Na Gong, Jing‐Wei Lai, Kai‐Ming Su, Lu‐Yang Wang, Hui Wang, Shan‐Kai Yin, Hao He, Hai‐Bo Shi   +13 more
wiley   +1 more source

The Toxic Legacy of Ammunition Lead (Pb) from Big Game Hunting in Sweden. [PDF]

Bull Environ Contam Toxicol
Arnemo JM, Singh NJ, Thomas VG, Fuchs B, Widemo F, Malmsten J, Hampton JO.   +6 more
europepmc   +1 more source

Butyrate ameliorates acute‐on‐chronic liver failure by regulating macrophage polarization

iMetaOmics, EarlyView.
Multi‐omics profiling identifies progressive microbiota‐metabolism‐immunity axis dysfunction in acute‐on‐chronic liver failure (ACLF), characterized by gut dysbiosis, reduced butyrate production, intestinal barrier disruption, microbial translocation, and pro‐inflammatory macrophage polarization, thereby exacerbating hepatic inflammation and fibrosis ...
Jing Xiao, Hang You, Zongyi Liu, Yong Sun, Yu Zhang, Li Wei, Ning Ling, Hong Ren, Shiying Li, Peng Hu, Mingli Peng   +10 more
wiley   +1 more source

Behavioural responses of Neotropical raptors to drone approaches to nests. [PDF]

Sci Rep
Aguiar-Silva FH, Junqueira TG, Rivas-Fuenzalida T, Zuluaga S, Kohn S, Restrepo-Cardona JS, Blanco-Márquez PA, Giraldo-Amaya M, Sanaiotti TM, Banhos A, Tuyama CA, Burgos-Andrade K, Orizano D, Narváez F, Encabo M, de Carvalho GDM, Aparicio K.   +16 more
europepmc   +1 more source

An Unattainable Emotional Advantage? Supervisors' Perceptual Biases in the Relationship Between Emotional Understanding Ability and Performance Ratings for Female Employees

Journal of Organizational Behavior, EarlyView.
ABSTRACT Empathy is increasingly valued at workplaces as it facilitates interpersonal relationships, collaboration, and team functioning. Accordingly, organizations increasingly observe and recognize employees' emotional understanding (EU) ability—a key foundation of empathy—as an important dimension of individual merit in performance evaluations.
Hanbo Shim, Myeong‐Gu Seo, Joo Hun Han, Sirkwoo Jin   +3 more
wiley   +1 more source

“Menopausal, Depleted, and Nostalgic”: The Bittersweet Effects of Menopause for Women Leaders

Journal of Organizational Behavior, EarlyView.
ABSTRACT Menopause is a natural but underexamined female experience in work settings, with significant implications for women in leadership positions. Drawing on self‐regulation perspectives, we develop a conceptual model examining how menopausal symptom severity shapes women leaders' experiences at work.
Olga Epitropaki, Maria Kakarika
wiley   +1 more source

Terazosin Attenuates Neuronal Pyroptosis by Regulating the Mitochondrial ROS/NLRP3 Inflammasome Axis Through Mitophagy in Cerebral Ischemia–Reperfusion Injury

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cerebral ischemia–reperfusion injury (CI/RI) is a major cause of secondary neuronal damage following ischemic stroke. This study investigated whether terazosin (TZ) exerts neuroprotective effects by regulating mitophagy and the reactive oxygen species (ROS)/NOD‐like receptor protein 3 (NLRP3) inflammasome axis.
Wei Wang, Xin‐Yue Han, Li‐An Huang, Yu‐Sheng Zhang, Heng Meng, An‐Ding Xu   +5 more
wiley   +1 more source

Photograph of Ada Marie Eagle and Bryan M. Eagle

A black & white photo of Ada Marie Eagle and her brother Bryan M ...

core  

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá, Ladislav Androvič, Marcela Filipová, Michal Pechar, Richard Laga   +4 more
wiley   +1 more source

Using Ongoing Wildlife Surveillance Programs to Monitor Antibiotic Resistant Bacteria in the Environment. [PDF]

Environ Microbiol Rep
Rincón-Gracia M, Börjesson S, Söderlund R, Woksepp H, Neimanis A, Uhlhorn H, Rosendal T, Winlund D, Uddströmer H, Järhult JD, Bonnedahl J.   +10 more
europepmc   +1 more source