Results 171 to 180 of about 47,672 (294)

Habitat imprinting in breeding territory selection of a long-lived bird of prey. [PDF]

J Anim Ecol
Penttinen I, Nebel C, Laaksonen T.
europepmc   +1 more source

Stage‐Associated Microglial Subpopulations and Dynamics in Vascular Pathogenesis of Oxygen‐Induced Retinopathy

Cell Proliferation, EarlyView.
In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma, Ziye Chen, Baoyi Liu, Wen Ding, Runping Duan, Kangjie Kong, Zhuojun Xu, Jizhu Li, Jiali Ru, Dianlei Guo, Xiaoyue Wei, Yaping Liu, Zhuangling Lin, Yang Meng, Yuan Liu, Lan Jiang, Zitong Chen, Rebiya Tuxun, Chinling Tsai, Chunqiao Liu, Tao Li   +20 more
wiley   +1 more source

Supplementary winter feeding is associated with higher recruitment rates in a population of a scavenging bird of prey. [PDF]

Oecologia
Nebel C, Penttinen I, Laaksonen T.
europepmc   +1 more source

Hepatocyte TrkB Acts as a Gatekeeper Against MASH‐Related Liver Fibrosis by Suppressing the TGFβ/CCL2 Axis and Macrophage Infiltration

Cell Proliferation, EarlyView.
Hepatocyte TrkB is identified as a critical gatekeeper against MASH‐related fibrosis. Mechanistically, TrkB inhibits the TGFβ/SMAD3/FOS axis to suppress CCL2 secretion, thereby blocking pathogenic macrophage recruitment and ameliorating liver fibrosis.
Yueying Chen, Jiayi Wei, Shuxuan Li, Kefan Yin, Heming Wang, Yicheng Zhao, Shuqiang Weng, Xizhong Shen, Guangqi Song, Changfeng Zhu, Qunyan Yao, Ling Dong   +11 more
wiley   +1 more source

A Curcumin‐Derived HSP70 Inhibitor Disrupts Lysosomal Function to Suppress Triple‐Negative Breast Cancer Progression

Cell Proliferation, EarlyView.
Novel curcumin‐derived M4 binds HSP70's ATPase domain, disrupting HSP70‐mediated lysosomes‐autophagy pathway to inhibit TNBC growth and metastasis, and synergizes with paclitaxel for potent combination therapy. ABSTRACT Structural modification of curcumin yielded a novel series of 1,4‐pentadien‐3‐one oxime ether derivatives, among which compound M4 ...
Zijian Li, Wanxia Wang, Yuxin Zhou, Tao Zeng, Jian Liu, Yingjie Qing, Xuan Han   +6 more
wiley   +1 more source

Using a Multi-Tracer Approach to Examine Perfluoroalkyl Substance Sources and Dietary Exposure Pathways in Pacific Bald Eagles. [PDF]

Environ Sci Technol
Kesic R, Elliott JE, Lamont M, Lee SL, Cheng KM, Maisonneuve F.   +5 more
europepmc   +1 more source

A White-tailed Sea-eagle and Been Geese

Japanese Journal of Ornithology, 1960
openaire   +2 more sources

Advancing the understanding of the human dimensions of Eurasian lynx reintroduction in Scotland

Conservation Science and Practice, EarlyView.
To identify perceived impacts of a lynx reintroduction among stakeholders and to explore factors shaping these perceptions, we conducted 34 unstructured interviews with stakeholders within and in potentially suitable habitat for a lynx reintroduction and surrounding areas in Scotland.
Faye L. Whiley, Daniel J. Ingram, Robert D. Fish, Douglas C. MacMillan, Joseph Tzanopoulos   +4 more
wiley   +1 more source

RNF13 is a previously undescribed interactor of iduronate 2‐sulfatase that modifies its glycosylation and maturation

The FEBS Journal, EarlyView.
Iduronate 2‐sulfatase (IDS; purple) is expressed as a precursor protein that goes through multiple steps of maturation, modification, and trafficking to become an active lysosomal enzyme that degrades glycosaminoglycans. Our study shows that the transmembrane ubiquitin ligases RNF13 (orange) and RNF167 (pink) heterodimerize, affecting IDS intracellular
Valérie C. Cabana, Antoine Y. Bouchard, Audrey M. Sénécal, Laurent Cappadocia, Marc P. Lussier   +4 more
wiley   +1 more source

Use of Citizen Science to Determine Prey Partitioning Between Two Coastal Raptors. [PDF]

Ecol Evol
Biggs L, Baxter GS, Debus SJS, Finch N, Riggs A, Houweling H, Appleby M, Murray PJ.   +7 more
europepmc   +1 more source