Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump +10 more
wiley +1 more source
Myliobatid Ray Gliding Dynamics: Experimental Tests of Body Shape and Tail Length on Stability. [PDF]
Cooper SB +3 more
europepmc +1 more source
Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf +7 more
wiley +1 more source
Sex affects the nestling diet of a large aerial predator of the Andes. [PDF]
Restrepo-Cardona JS +7 more
europepmc +1 more source
Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo +6 more
wiley +1 more source
Mitochondrial Genome Analysis of Philippine Eagles (<i>Pithecophaga jefferyi</i> Ogilvie-Grant 1896) From the Greater Mindanao Faunal Region. [PDF]
Bacus MG +11 more
europepmc +1 more source
ABSTRACT This study examines how artificial intelligence (AI) reshapes gender dynamics in workplace negotiations. Adopting a technofeminist lens, we conceptualize gender–technology relations as mutually shaping and fluid. Using a convergent mixed‐methods design, participants negotiated job offers with an AI chatbot recruiter.
Sue H. Moon, Jing Betty Feng
wiley +1 more source
Avian Diversity in the Ethiopian Orthodox Churches and Monasteries in the Case of Jer Silase Monastery in North Shoa Zone, Ethiopia. [PDF]
Desalegn T +3 more
europepmc +1 more source
Unmothered at Work: Organizational Silence Around Reproductive Loss
ABSTRACT An identity transition refers to changes in self‐concept that can result from professional or personal shifts. Although organizations increasingly support institutionally legible and culturally normative nonwork transitions, others remain professionally stigmatized or culturally unspeakable.
Katrina M. Brownell
wiley +1 more source
Descriptive histological analysis of the upper, lower, and third eyelids and the conjunctiva-associated lymphoid tissue in birds of prey. [PDF]
Klećkowska-Nawrot JE +4 more
europepmc +1 more source

