Results 181 to 190 of about 2,829,195 (234)

Rapid and Efficient Affinity Isolation of Engineered Extracellular Vesicles Encapsulating Functional Proteins via Internal Twin‐Strep Tetraspanin Tagging

open access: yesSmall, EarlyView.
Structure‐guided internal twin‐Strep tagging of the tetraspanins CD63 or CD9 enables rapid and efficient antibody‐free affinity isolation of engineered extracellular vesicles (EVs) using Strep technology while allowing luminal protein loading. The approach removes over 96% of contaminants, separates tagged EVs from coexisting viral particles, and ...
Minh‐Tu Pham   +14 more
wiley   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

open access: yesSmart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang   +8 more
wiley   +1 more source

The Impact of Anthem Protests, MAGA, and BLM on NFL Attendance

open access: yesSouthern Economic Journal, EarlyView.
ABSTRACT On September 1, 2016, Colin Kaepernick first took a knee during the San Francisco 49ers' final preseason game. The protest quickly became league‐wide, and inspired similar actions by players in the WNBA, NWSL, NBA, college football and other professional sports.
Oskar Harmon, Jungbin Hwang
wiley   +1 more source

Use of Citizen Science to Determine Prey Partitioning Between Two Coastal Raptors. [PDF]

open access: yesEcol Evol
Biggs L   +7 more
europepmc   +1 more source

HSPE1 deficiency underlies the crosstalk between metabolic dysfunction‐associated steatotic liver disease and age‐related macular degeneration

open access: yesVIEW, EarlyView.
Rare‐earth ions act as multifunctional modifiers in perovskite solar cells by improving charge transport, suppressing oxygen vacancies, passivating defects, promoting grain growth, and enabling redox‐mediated stabilization. In addition, RE‐doped layers can expand spectral utilization through upconversion and downconversion, thereby enhancing light ...
Jiaqi Meng   +9 more
wiley   +1 more source

Gastritis and age‐related macular degeneration: Potential roles of metabolomic dysregulation and photoreceptor alterations

open access: yesVIEW, EarlyView.
Abstract Age‐related macular degeneration (AMD) is a degenerative retinal disorder and a leading cause of global visual impairment, yet effective treatments remain limited. While gastritis is a prevalent clinical condition among older populations and has been associated with adverse effects on the central nervous system, its potential association with ...
Jingxin Zhou   +5 more
wiley   +1 more source

Endangered Steppe Eagle (<i>Aquila nipalensis</i>) (Aves, Accipitriformes, Accipitridae) genome and mitogenome assembly: A resource for molecular evolution and comparative genomics. [PDF]

open access: yesZookeys
Buthasane W   +10 more
europepmc   +1 more source

Hunting as anthropogenic sink of biomass or source of carrion? A brief case study based on German hunting bags

open access: yesWildlife Biology, EarlyView.
Dead biomass is a crucial nutrient source for ecosystems. Although hunting residues can subsidize numerous scavenging organisms and are known to drive important zoogeochemical processes at very different scales in the ecosystem, this has received little attention.
Jörg Beckmann   +3 more
wiley   +1 more source

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