Results 201 to 210 of about 16,338 (281)

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

The FEBS Journal, EarlyView.
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump, Leja Perne, Špela Koren, Eva Jarc Jovičić, Nastja Feguš, Carina Pinto Kozmus, Michele Wölk, Kristyna Brejchova, Maria Fedorova, Ondrej Kuda, Toni Petan   +10 more
wiley   +1 more source

Positive and negative impacts of electrical infrastructure on animal biodiversity: A systematic review. [PDF]

Oecologia
Bennett AJ, Watson DM, Watson MJ.
europepmc   +1 more source

Resistance‐exercise‐induced stress intervenes in TGF‐β signaling by cooperatively downregulating nuclear αB‐crystallin and SMAD4 in human skeletal muscle fibers

The FEBS Journal, EarlyView.
Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf, Cassandra Duda, Tihomir Kostov, Patrick Diel, Käthe Bersiner, Wilhelm Bloch, Sebastian Gehlert, Daniel Jacko   +7 more
wiley   +1 more source

The return of raptors to Scotland's skies: Investigating the diets of reintroduced red kites and white-tailed eagles using stable isotopes. [PDF]

PLoS One
Waterman J, Black S, Sykes N, Kitchener AC, Mills WF, Fellowes MDE.   +5 more
europepmc   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

The FEBS Journal, EarlyView.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo, Bastien Morlet, Luc Negroni, Orsolya Mózner, Balázs Sarkadi, Gilles Travé, Gergo Gogl   +6 more
wiley   +1 more source

Avian diversity and ethnoornithology in Pawukon - a 19th-Century Javanese manuscript : informing contemporary conservation of vulnerable species. [PDF]

J Ethnobiol Ethnomed
Putri RA, Ekowati VI, Dwiadmojo GN.
europepmc   +1 more source

RNF13 regulates the endolysosomal pathway through interaction with the small GTPase Arl8B

The FEBS Journal, EarlyView.
The E3 ubiquitin ligase RNF13 functions as a regulatory scaffold, organizing Arl8B‐dependent complexes and tuning downstream signaling that controls endolysosomal organization and trafficking. In this model, wild‐type RNF13 associates with Arl8B on endolysosomes, whereas Arl8B (E22D/F55A) or RNF13 (L244A) variants weaken complex assembly, potentially ...
Audrey M. Sénécal, Valérie C. Cabana, Antoine Y. Bouchard, Laurent Cappadocia, Marc P. Lussier   +4 more
wiley   +1 more source

A novel antiviral strategy targeting human metapneumovirus through pH modulation in human airway epithelial cells. [PDF]

J Gen Virol
Daniels IA, Gaston B, Saunders J, Smith L, Whitlow T, Tilston NL, Relich RF, Lunel A, Davis MD.   +8 more
europepmc   +1 more source

Technofeminism at Work: Artificial Intelligence‐Mediated Negotiations and the Reproduction of Gendered Communication Norms

Gender, Work &Organization, EarlyView.
ABSTRACT This study examines how artificial intelligence (AI) reshapes gender dynamics in workplace negotiations. Adopting a technofeminist lens, we conceptualize gender–technology relations as mutually shaping and fluid. Using a convergent mixed‐methods design, participants negotiated job offers with an AI chatbot recruiter.
Sue H. Moon, Jing Betty Feng
wiley   +1 more source

Prevalence and local transmission of haemosporidian (Haemosporida) parasites in nestlings of birds of prey (Aves, Accipitriformes) in the temperate forests in Lithuania. [PDF]

Int J Parasitol Parasites Wildl
Bukauskaitė D, Romeiro Fernandes Chagas C, Duc M, Kazak M, Treinys R.   +4 more
europepmc   +1 more source