Myeloid Cell-Restricted Insulin Receptor Deficiency Protects Against Obesity-Induced Inflammation and Systemic Insulin Resistance [PDF]
, 2010 A major component of obesity-related insulin resistance is the establishment of a chronic inflammatory state with invasion of white adipose tissue by mononuclear cells.
Blüher, Matthias +8 more
core +3 more sources
The role of the cytoplasmic redox potential in the control of fatty acid synthesis from glucose, pyruvate and lactate in white adipose tissue [PDF]
, 1970 Mitchell L. Halperin, B. H. Robinson
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Impact of white adipose tissue in AD pathology
, 2021 Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
Bettinetti-Luque, Miriam +7 more
openaire +2 more sources
Advanced Science, EarlyView.Biosynthesis rates of 13 FFAs are quantitatively calculated in 15 tissues from glucose and an analytical framework to quantitatively calculate inter‐tissue communications of fatty acids between the liver and other tissues is developed. Moreover, the approach is extended to aging condition and a system‐wide decline of fatty acid synthesis in peripheral ...
Beizi Xing +4 more
wiley +1 more source
UCP1 in Brite/Beige Adipose Tissue Mitochondria Is Functionally Thermogenic
Cell Reports, 2013 The phenomenon of white fat “browning,” in which certain white adipose tissue depots significantly increase gene expression for the uncoupling protein UCP1 and thus supposedly acquire thermogenic, fat-burning properties, has attracted considerable ...
Irina G. Shabalina +5 more
doaj +1 more source
WHITE ADIPOSE TISSUE (WAT) AND HEAT PRODUCTION IN THE NEWBORN RABBIT [PDF]
, 1977 T Helm +4 more
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Advanced Science, EarlyView.Patients with osteoporosis face a higher risk of bone injury, mainly due to weakened osteogenic differentiation and bone formation, along with increased osteoclast differentiation and bone resorption activity, leading to bone homeostasis imbalance.
Xinhui Wu +13 more
wiley +1 more source
Sex matters: The effects of biological sex on adipose tissue biology and energy metabolism
Redox Biology, 2017 Adipose tissue is a complex and multi-faceted organ. It responds dynamically to internal and external stimuli, depending on the developmental stage and activity of the organism.
Teresa G. Valencak +2 more
doaj
Studies on the conversion of pyruvate into fatty acids in white adipose tissue. Effects of insulin, alloxan-diabetes and starvation [PDF]
, 1971 Mitchell L. Halperin
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Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
Advanced Science, EarlyView.This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu +9 more
wiley +1 more source